ADC值及相对ADC值鉴别诊断颈部淋巴瘤与转移性淋巴结  

ADC and relative ADC in differential diagnosis of lymphoma and metastasis in cervical lymph nodes

作　　者：钟婧[1] 陈翠芳 陈英[1] 林家豪[1] 鲍道亮[1] 陈韵彬[1] ZHONG Jing;CHEN Cuifang;CHEN Ying;LIN Jiahao;BAO Daoliang;CHEN Yunbin(Department of Radiology,Fujian Cancer Hospital,Fujian Medical UniversityCancer Hospital,Fuzhou 350014,China)

机构地区：[1]福建省肿瘤医院福建医科大学附属肿瘤医院放射诊断科,福建福州350014

出　　处：《中国医学影像技术》2018年第6期846-849,共4页Chinese Journal of Medical Imaging Technology

基　　金：福建省科技厅引导性项目(2016Y0018)

摘　　要：目的探讨ADC值和相对ADC值(rADC值)鉴别诊断颈部淋巴瘤与转移性淋巴结的价值。方法对69例淋巴瘤累及颈部淋巴结患者(淋巴瘤组)及66例颈部淋巴结转移患者(转移组)行MR检查,测量淋巴结及咬肌的ADC值,并计算淋巴结rADC值。分析观察者间测量的一致性,比较2组ADC值及rADC值差异。绘制ROC曲线,评价ADC和rADC值鉴别诊断淋巴瘤与转移淋巴结的效能。结果2名医师测量淋巴结及咬肌ADC值的一致性好(ICC均>0.9),淋巴瘤组ADC值及rADC值均明显低于转移组(P均<0.05)。ADC阈值取0.702×10^(-3) mm^2/s时,其鉴别诊断淋巴瘤与转移淋巴结的敏感度及特异度为98.48%及76.81%;rADC阈值取0.584时,其鉴别诊断淋巴瘤与转移淋巴结的敏感度及特异度为89.39%及84.06%。结论 ADC值及rADC值均能有效鉴别诊断颈部淋巴瘤与转移性淋巴结。Objective To investigate the value of MR apparent diffusion coefficient（ADC）and relative apparent diffusion coefficient（rADC）in differential diagnosis of lymphoma and metastasis in cervical lymph nodes.Methods Totally 69 patients with lymphoma（lymphoma group）and 66 patients with cervical lymph nodes metastasis（metastasis group）underwent MR examination.ADC values of lymph nodes and the right masseter muscle were measured,and rADC values were calculated.The consistency between two observers was evaluated.The differences of ADC value and rADC value were compared between the two groups.The efficacy of ADC value and rADC value in differential diagnosis of lymphoma and metastasis in cervical lymph nodes was analyzed with ROC curve.Results The consistency between two observers was excellent（all ICC0.9）.Both ADC and rADC values of lymphoma group were significantly lower than those of metastasis group（all P〈0.05）.Taken ADC and rADC values as 0.702×10-3 mm2/s and 0.584,the sensitivity and specificity was98.48% and 89.39%,76.81% and 84.06%,respectively.Conclusion ADC and rADC values are useful in discriminating lymphoma from metastatic lymph nodes.

关 键 词：磁共振成像 淋巴瘤 表观扩散系数 淋巴转移 

分 类 号：R445.2[医药卫生—影像医学与核医学] R322.27[医药卫生—诊断学]