可吸收止血流体明胶在腰椎后路手术中的临床应用研究  

Application of absorbable Surgiflo haemostatic matrix in posterior lumbar interbody fusion

作　　者：官志平 吴镇权[1] 温健[1] 邱瑞珊 王文豪[1] 石岩[1] 于滨生[1] GUAN Zhiping;WU Zhenquan;WEN Jian;QIU Ruishan;WANG Wenhao;SHI Yan;YU Binsheng(Department of Spinal Surgery,Peking University Shenzhen Hospital,Shenzhen 518036,China;Department of Surgery,Shenzhen People＇s Hospital Longhua Branch,Shenzhen,Guangdong 518109,China)

机构地区：[1]北京大学深圳医院脊柱外科,深圳518036 [2]深圳市人民医院龙华分院外一科,深圳518109

出　　处：《岭南现代临床外科》2018年第3期295-297,共3页Lingnan Modern Clinics in Surgery

摘　　要：目的探讨可吸收止血流体明胶在腰椎后路椎间融合术中控制出血的有效性和安全性。方法选取我科2016年10月至2017年10月期间因腰椎管狭窄症,行单节段腰椎后路减压椎间融合植骨内固定术的患者共96例,分为试验组和对照组,每组分别为48例。对照组采用常规外科手术方法止血,试验组术中除常规外科止血外,同时使用可吸收止血流体明胶。通过对比两组患者的手术时间、术中出血量、术后引流量,术后感染的发生情况等综合评价两组患者的治疗效果。结果试验组应用可吸收止血流体明胶后,其术中出血量(180.7±15.6)mL、手术时间(95.6±13.8)min,均少于对照组术中出血量(216.8±19.2)mL、手术时间(103.7±18.9)min,差异有统计学意义(P<0.05);试验组术后第1、2、3天的引流量分别为(186.8±29.2)mL、(286.7±27.1)mL、(320.7±30.2)mL,与对照组(210.8±36.1)mL、(315.5±20.5)mL、(372.8±22.2)mL相比,差异有统计学意义(P<0.05)。术后伤口发生感染的情况,试验组发生率为2/48,对照组发生率为3/48,无统计学差异(P>0.05)。结论流体明胶可减少手术时间、术中出血量以及术后引流量,并不增加伤口感染的风险。它是一种安全、有效的止血剂,在腰椎后路手术中有其应用价值。Objective To observe the clinical hemostatic efficacy and safety of absorbable Surgiflo haemostatic matrix（Surgiflo）in posterior lumbar interbody fusion（PLIF）. Methods A total of 96 patients performed PLIF in our hospital from Oct. 2016 to Oct. 2017,were recruited in our study.Members were divided into two groups,experimental group（n=48）and control group（n=48）. Surgiflo were used in experimental group,but not in control group. The volume of blood loss,operative duration,the seroma volume of drainage at 24 h,48 h,72 h after operation,and wound infection were compared between two groups. Results Compared with control group,the volume of blood loss,operative duration,the seroma volume of drainage at 24 h,48 h,72 h after operation in experimental group was significantly less（P〈0.05）. There was no significant difference between the two groups in the wound infection,wound and hospital stay after surgery（P〉0.05）. Conclusion Surgiflo has good hemostatic effect in PLIF,and can reduce the volume of blood loss,operative duration,the seroma volume of drainage.

关 键 词：后路腰椎椎间融合术 腰椎管狭窄症 可吸收止血流体明胶 

分 类 号：R681.5[医药卫生—骨科学]