多导睡眠图及CT在轻度认知损害老年病人中的应用研究  

Application of Polysomnography and CT in the Elderly Patients with Mild Cognitive Impairment

作　　者：王超[1] 耿彩虹[2] 任月勤[3] 王小虎 WANG Chao;GENG Cai-hong;REN Yue-qin(Department of Sleep Medicine,Second Affiliated Hospital of Xinxiang Medical University,Xinxiang 453002,Henan Province,China)

机构地区：[1]新乡医学院第二附属医院睡眠医学科,河南新乡453002 [2]新乡医学院第二附属医院精神科,河南新乡453002 [3]河南省中医院放射科,河南郑州450002 [4]河南省省立医院心血管内科,河南郑州450002

出　　处：《中国CT和MRI杂志》2018年第7期55-58,共4页Chinese Journal of CT and MRI

基　　金：河南省卫计委骨干人才培养课题(2014-ZQN-JC-87)

摘　　要：目的研究多导睡眠图及CT在轻度认知损害老年病人中的应用。方法将45例轻度认知功能损害的患者设为研究组,进行多导睡眠图及CT检查;将45例认知功能正常的老年人设为对照组,采取经颅多普勒超声(TCD)检查。比较两组的匹兹堡睡眠质量指数(PSQI)、失眠严重指数(ISI)、血流动力学指标、蒙特利尔认知功能评分量表(Mo CA量表)、密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)。结果研究组PSQI和ISI评分显著高于对照组,差异均有统计学意义(P<0.01)。对照组MCA-IP、ACA-PI明显大于研究组,差异均有统计学意义(P<0.01);对照组的Mo CA量表总分(25.50±3.57),明显大于研究组Mo CA量表总分(20.06±3.66),差异有统计学意义(P<0.01)。两组MCAVm、ACA-Vm进行比较,差异均无统计学意义(P>0.05)。对照组的HAMA、HAMD评分明显小于研究组,差异均有统计学意义(P<0.05)。结论多导睡眠图及CT可有效反应轻度认知损害老年病人的脑血管情况和睡眠情况,为临床治疗和控制病情提供科学依据,从而对老年痴呆起到预防作用。Objective To study the application of polysomnography and CT in elderly patients with mild cognitive impairment. Methods A total of 45 patients with mild cognitive impairment were selected as the study group, and given polysomnography and CT examination. Another 45 elderly patients with normal cognitive function were selected as the control group, and given transcranial Doppler（TCD） examination. Pittsburgh sleep quality index（PSQI）, insomnia severity index（ISI）, Montreal cognitive function and hemodynamics index, score scale（Mo CA scale）, Milton Anxiety Scale（HAMA）, Hamilton Depression Scale（HAMD） were compared between the two group.Results The scores of PSQI and ISI in the study group were significantly higher than those in the control group, and were statistically significant（P〈0.01）. The MCA-IP and ACAPI in the control group were significantly higher than those in the study group, and there were statistically significant（P〈0.01）. MCA-Vm and ACA-Vmin the two groups were no significant difference（P〉0.05）. Th score of the Mo CA scale（25.50＋3.57） in the control group was significantly higher than the score of the Mo CA scale（20.06＋3.66） in the study group, and was statistically significant（P〈0.01）. The scores of HAMA and HAMD in the control group were significantly lower than those in the study group,and were statistically significant（P〈0.05）. Conclusion Polysomnography and CT can effectively reflect cerebrovascular status and sleep condition in elderly patients with mild cognitive impairment, and provide a scientific basis for clinical treatment and control of disease and play a preventive role in Alzheimer＇s disease.

关 键 词：多导睡眠图 CT 轻度认知损害 睡眠质量 

分 类 号：R714.252[医药卫生—妇产科学]