正常青年人左心室长轴心肌应变特征的MRI研究  

MRI Study of Strain Feature of Left Ventricular Long-axis Myocardium in Normal Young Adults

作　　者：李梦露[1] 席晓旭 程流泉[1] 李俊超[2] 董蔚[2] 陈韵岱[2] 智光[2] LI Menglu;XI Xiaoxu;CHENG Liuquan;LI Junchao;DONG Wei;CHEN Yundai;ZHI Guang(Department of Radiology,PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院放射诊断科,北京100853 [2]解放军总医院心内科,北京100853

出　　处：《中国医学影像学杂志》2018年第4期258-263,共6页Chinese Journal of Medical Imaging

基　　金：国家自然科学基金面上项目(81471660)

摘　　要：目的运用特征追踪(FT)技术测量正常青年志愿者心脏MRI电影成像上心肌长轴各节段的纵向和横向的应变和位移参数,分析左心室长轴应变运动的规律,建立纵向和横向的应变和位移的峰值和达峰时间(TTP)的参考值范围。资料与方法采用PhilipsMultiva 1.5T MRI扫描仪采集29例24~34岁健康志愿者的心脏电影图像,包括左心室长轴、左心室流出道和四腔心3个典型长轴层面。采用心肌特征追踪软件TOMTEC对MRI电影图像进行分析,获得心脏除心尖外16个AHA节段的纵向和横向应变、位移的峰值与TTP,分析各参数在平面、层面和节段之间的规律。结果纵向应变、纵向位移和横向应变的TTP在心肌各节段之间均具有一致性,(41.24±12.51)%RR间期,为恒定指标。纵向位移的峰值表现为心尖(2.56±0.89)mm<中部(6.09±2.03)mm<心底(8.07±2.05)mm,横向位移的峰值表现为心尖(4.57±1.18)mm<中部(5.65±0.84)mm<心底(8.48±1.18)mm,与视觉观察的心脏几何形变一致。纵向应变在2CH-3CH-4CH平面具有一致性,其峰值参考值为(-22.46±13.19)%;而横向应变在不同平面间的峰值缺乏一致性。结论左心室不同平面的纵向应变具有一致的峰值和TTP,具有良好的参考价值。Purpose To measure the longitudinal and transverse strain and displacement parameters of each segment of long axis myocardium on cardiac MRI film images of normal young volunteers using feature tracking technique （FT）, and to analyze the regularity of left ventricular long axis strain and establish peak and time to peak （TTP） reference range concerning the longitudinal and transverse strain and displacement. Materials and Methods Cardiac film images of 29 healthy volunteers aged 24 to 34 were collected using Philips Multiva 1.5T MRI scanner, including three typical long axis planes of the left ventricular long axis, left ventricular outflow tract, and four-chamber view. The MRI film images were analyzed drawing on myocardial feature tracking software TOMTEC, and the peak value and TTP of longitudinal and transverse strain and displacement of the 16 AHA segments excluding apex cordis were obtained thereby. The regularity of each parameter concerning the plane, layer, and segment was summarized and analyzed. Results The TTP of longitudinal strain, longitudinal displacement and transverse strain were consistent among each myocardial segment, which was a constant indicator in （41.24±12.51） % RR interphase. The peak value of longitudinal displacement was represented by apex cordis （2.56±0.89） mm 〈 middle （6.09±2.03） mm 〈 cardiac base （8.07±2.05） mm, and the peak value of transverse displacement was manifested as apex cordis （4.57±1.18） mm 〈 middle （5.65±0.84） mm 〈 cardiac base （8.48 ±1.18） mm, which was consistent with cardiac geometric deformation visually observed. The longitudinal strain showed consistency on 2CH-3CH-4CH plane, whose peak reference value was （-22.46±13.19）%; while the peak value of transverse strain displayed no consistency on different planes. Conclusion The longitudinal strain of the left ventricular on different planes has consistent peak value and TTP, suggesting good reference value.

关 键 词：磁共振成像 电影 心肌 心室功能 左 心肌收缩 志愿工作者 成年人 

分 类 号：R445.2[医药卫生—影像医学与核医学] R542.2[医药卫生—诊断学]