心脏瓣膜置换术治疗大左心室心脏瓣膜病的临床疗效  

Clinical Curative Effect of Cardiac Valve Replacement for the Treatment of Cardiac Valve Disease with Giant Left Ventricle

作　　者：陈建成[1] 梁忠诚[1] 李欣[2] CHEN Jiancheng1, LIANG Zhongeheng1, LI Xin2(1 Department of Cardiothoraeic Surgery, Xinhui District People ＇s Hospital, Jiangmen 529100, China; 2Department of Cardiac Surgery, Guangdong General Hospital, Guangzhou 510080, China)

机构地区：[1]江门市新会区人民医院心胸外科,广东江门529100 [2]广东省人民医院心外科,广东广州510080

出　　处：《临床医学工程》2018年第6期805-806,共2页Clinical Medicine & Engineering

摘　　要：目的探讨心脏瓣膜置换术治疗大左心室心脏瓣膜病的临床效果。方法选取79例大左心室心脏瓣膜病患者,行心脏瓣膜置换术治疗。检测比较患者治疗前、治疗后2周、治疗后6个月的心功能指标(LVEDD、LVESD、LAD、LVEF)和心功能NYHA分级,并统计患者治疗期间的并发症发生情况。结果治疗前、治疗后2周和治疗后6个月,患者的平均LVEDD、LVESD、LAD、LVEF随着治疗的进行逐渐降低,NYHA分级为Ⅰ级或Ⅱ级的患者占比逐渐升高,NYHA分级为Ⅲ级或Ⅳ级的患者占比逐渐降低,各时点比较差异均有统计学意义(P<0.05)。79例患者中,并发症发生率为72.15%(57/79),死亡率为3.80%(3/79)。结论心脏瓣膜置换术治疗大左心室心脏瓣膜病能显著改善患者的心功能,术后早期死亡率较低。Objective To explore the clinical effect of cardiac valve replacement for the treatment of cardiac valve disease with giant left ventricle. Methods＇ 79 cases of patients with cardiac valve disease with giant left ventricle were selected. All patients were treated with cardiac valve replacement. Before treatment, 2 weeks after treatment and 6 months after treatment, the cardiac function indicators including LVEDD, LVESD, LAD and LVEF, and NYHA classification of cardiac function were detected, and the incidences of complications during treatment were calculated. Results Before treatment, 2 weeks after treatment and 6 weeks after treatment, patients＇ average LVEDD, LVESD, LAD and LVEF decreased gradually with the progress of the treatment, the proportion of NYHA grade I and grade II increased gradually, and the proportion of NYHA grade ii1 and grade IV decreased gradually; The comparison among each time points had significant differences （P〈0.05）. Among 79 cases of patients, the incidence of complications was 72.15% （57/79）, and the death rate was 3.80% （3/79）. Conclusions Cardiac valve replacement for the treatment of cardiac valve disease with giant left ventricle can significantly improve patients, cardiac function, and has lower early postoperative mortalily rate.

关 键 词：心脏瓣膜置换术 大左心室心脏瓣膜病 临床疗效 安全性 

分 类 号：R542.5[医药卫生—心血管疾病]