自噬-溶酶体系统与慢性肾衰竭营养不良  

Autophagy-Lysosome System and Chronic Renal Failure Malnutrition

作　　者：刘佳配 刘华锋 LIU Jiapei, LIU Huafeng(Guangdong Medical University, Zhanjiang 524000, China)

机构地区：[1]广东医科大学,广东湛江524000

出　　处：《临床医学工程》2018年第6期835-836,共2页Clinical Medicine & Engineering

摘　　要：慢性肾衰竭患者普遍存在蛋白质-能量营养不良,主要临床表现为肌肉萎缩;近年来研究发现自噬-溶酶体体系在肌肉萎缩中起到重要作用。现查阅相关文献,对自噬-溶酶体系统在慢性肾衰竭营养不良中的作用作一综述,为今后的临床治疗提供参考。Protein energy malnutrition is common in patients with chronic renal failure, and the main clinical manifestation is muscular atrophy. In recent years, it has been found that autophagy-lysosome system plays an important role in muscle atrophy. By consulting related literature, this review- summarized the role of autophagy-lysosome system in chronic renal failure malnutrition, so as to provide reference for future clinical treatment.

关 键 词：自噬-溶酶体系统 慢性肾衰竭 营养不良 肌肉萎缩 

分 类 号：R692.5[医药卫生—泌尿科学]