樱桃核提取物抗疲劳、耐缺氧及镇痛作用的研究  

Study on Anti-fatigue,Anti-anoxia and Analgesic Effects of Cherry Kernel Extract

作　　者：郭遥遥 刘洋[1] 王沙沙[1] 公衍玲[1] GUO Yaoyao;LIU Yang;WANG Shasha;GONG Yanling(College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 2GG042,Chin)

机构地区：[1]青岛科技大学化工学院,山东青岛266042

出　　处：《青岛科技大学学报（自然科学版）》2018年第4期28-32,共5页Journal of Qingdao University of Science and Technology:Natural Science Edition

基　　金：国家自然科学基金青年基金项目(81300281);山东省高校科技计划项目(J15LK12)

摘　　要：分别采用小鼠负重游泳和测定肝糖原、在缺氧状态下存活时间以及扭动身体次数,来研究抗疲劳、耐缺氧和阵痛的作用。抗疲劳实验中,水提取物组小鼠游泳力竭时间和肝糖原含量与乙醇提取物组比均增加,与空白对照组比有显著性差异(P<0.05);耐缺氧实验中,水提取物组小鼠存活时间与乙醇提取物组比均延长,与空白对照组相比有显著性差异(P<0.05);镇痛实验中,水提取物组与空白对照组比,小鼠扭体次数显著减少(P<0.05),中、大剂量组潜伏期显著增长(P<0.05),乙醇提取物组与空白对照组比无显著性差异。樱桃核水提取物具有显著的抗疲劳、耐缺氧及镇痛作用。To study anti-fatigue,anti-anoxia and analgesic effect of cherry kernel extract by loaded swimming and determination of liver glycogen,survival time under hypoxia,and twist frequency in mice,respectively.In the anti-fatigue experiments,the swimming time and the content of liver glycogen of the mice in the water extract group were significantly higher than ethanol extract group,showing significant differences compared with blank control group（P0.05）;In the anti-anoxia experiments,the survival time of the mice in the water extract group was significantly longer than ethanol extract group compared with control group（P 0.05）;In the analgesic experiments,compared with the blank control group,the twist frequency of mice in water extract group was significantly reduced（P0.05）.The latent period significantly increased in the mid and large dose groups（P0.05）.However,there had no significant differences between ethanol extract group and the blank control group.Cherry kernel water extract has significant anti-fatigue,anti-anoxia and anal-gesic effects.

关 键 词：樱桃核 抗疲劳 耐缺氧 镇痛 

分 类 号：R284.2[医药卫生—中药学]