磁共振T1rho成像在定量检测飞行人员早期椎间盘退变中的应用价值  

T1rho Imaging Quantification of Early Intervertebral Disc Degeneration in Pilots on 3.0T Magnetic Resonance

作　　者：张秀兰 钱勇[2] 田雨[2] 毕永民[2] ZHANG Xiulan;QIAN Yong;TIAN Yu(Department of Radiology,The First People＇s Hospital of Jingzhou,Jingzhou,Hubei Province 434000,P.R.Chin)

机构地区：[1]长江大学第一附属医院荆州市第一人民医院放射科,荆州434000 [2]空军总医院磁共振科,北京

出　　处：《临床放射学杂志》2018年第7期1177-1181,共5页Journal of Clinical Radiology

摘　　要：目的探讨3.0 T磁共振T1rho成像技术在定量检测飞行人员早期椎间盘退变的应用价值。方法对34名无腰痛症状的男性飞行人员行腰椎间盘MRI,同时采集矢状位常规T2WI及T1rho图像。将图像原始数据上传至工作站进行髓核T1rho值测定。依据T2WI常规矢状位图像按Pfirrmann标准对腰椎间盘退变进行分级,分析腰椎间盘髓核T1rho值与Pfirrmann分级、椎间盘层面、年龄及飞行时长的关系。结果各椎间盘T1rho值与Pfirrmann等级呈负相关（r=-0.901,P〈0.01）,PfirrmannⅠ~Ⅳ级间T1rho值差异有统计学意义（F=277.892,P〈0.01）;T1rho值与年龄呈负相关（r=-0.709,P〈0.01）,所有年龄组间T1rho值差异有统计学意义（t’=77.406,P〈0.01）。各水平椎间盘T1rho值无显著差异（P〉0.05）。不同飞行时长组间T1rho值差异有统计学意义（t＇=41.641,P〈0.01）。结论髓核T1rho弛豫时间与腰椎间盘退变程度、年龄及飞行时长均密切相关,与椎间盘层面无关;T1rho定量检测技术可能成为飞行人员早期椎间盘退变的一种有效检测工具。Objective To evaluate early intervertebral disc degeneration quantified by T1rho-and T2-weighted magnetic resonance imaging（ MRI） at 3. 0 T in asymptomatic pilots. Methods A total number of 34 asymptomatic male pilots underwent examination using a 3. 0 T MR scanner with an 8-channel CTL Target Array Coil. Both sagittal conventional T2-and T1rho-weighted images were acquired at every examination of lumbar disc. The original scan data was transferred to AW 4.5 workstation for analyses. The sagittal T1rho maps were reformatted for each disk. Mean T1rho values of the central disk space nucleus pulposus were determined by using post-processing software. The degenerative grade of each lumbar disc was assessed from T2-weighted images according to Pfirrmann degenerative grade. Bivariate correlation analysis was performed to compare T1rho values to the degenerative grade,disc space level,age and flight time of the pilots. Results T1rho values were significantly negatively correlated with Pfirrmann grade Ⅰ ~ Ⅳ（ r =-0. 901,P〈0. 01） and ages（ r =-0. 709,P〈0. 01）. There was a significant difference in T1rho values between Pfirrmann grade Ⅰ-Ⅳ（ F = 277. 892,P〈0. 01） and among all the age groups（ t＇ = 77. 406,P〈0. 01）. However,there was no significant difference in the T1rho values observed between each level（ P〉0. 05）. T1rho values were significantly pairwise different among the flight time groups（ t＇=41. 641,P〈0. 01）. Conclusion T1rho values of Lumbar intervertebral discs in pilots demonstrated significantly negative correlations with degenerative grade,age and flight time,except for disk space levels. T1rho may be potentially used as a valid clinical method in the quantitative diagnosis of early intervertebral disc degeneration in asymptomatic Pilots.

关 键 词：飞行人员 磁共振成像 T1rho 腰椎间盘退变 

分 类 号：R445.2[医药卫生—影像医学与核医学] R85[医药卫生—诊断学]