新型噻唑衍生物的合成及对Fe^(3+)的识别  

Synthesis of a novel thiazole derivative and its selective detection of Fe^(3+)

作　　者：刘天宝[1] 彭艳芬[1] 桂美芳[1] Liu Tianbao;Peng Yanfen;Gui Meifang(College of Chemical and Material Engineering,Chizhou University,Chizhou 24700)

机构地区：[1]池州学院化学与材料工程学院,池州247000

出　　处：《化工新型材料》2018年第7期131-134,共4页New Chemical Materials

基　　金：国家自然科学基金项目(21271035);安徽省教育厅自然科学基金重点项目(KJ2016A512);安徽省高校优秀青年人才支持计划重点项目(gxyqZD2016372);池州学院自然科学基金重点项目(2017ZRZ002)

摘　　要：以3-邻氯苯甲酰基-1-苯基硫脲和2-溴代苯乙酮为原料,设计合成了一种新型的噻唑衍生物2-邻氯苯甲酰亚氨基-3,4-二苯基-1,3-噻唑(CDT),并采用傅里叶变换红外光谱、核磁共振氢谱、核磁共振碳谱对其结构进行了表征。结果表明:化合物CDT可作为荧光探针选择性识别Fe^(3+),且几乎不受其他常见金属离子(Ag+,Al 3+,Ba^(2+),Ca^(2+),Cd^(2+),Co^(2+),Cu^(2+),Hg^(2+),K+,Mg^(2+),Na+,Pb^(2+),Zn^(2+))的干扰。探针CDT的荧光强度与Fe^(3+)的浓度(2×10^(-6)~6×10^(-5) mol/L)呈良好的线性关系,复相关系数R2为0.9965。CDT对Fe^(3+)检出限为9.7×10^(-7) mol/L,二者络合常数为3.3×104 L/mol,络合比为1∶1。A new thiazole derivative,2-o-chlorobenzoylimino-3,4-diphenyl-1,3-thiazole（CDT）,was prepared from 3-o-Chlorobenzoyl-1-phenylthiourea with 2-bromoacetophenone,and its structure was confirmed by FT-IR,1 H-NMR and 13 C-NMR.The results showed that the compound CDT exhibited the selective to Fe3＋,and other metal ions（Ag＋,Al 3＋,Ba2＋,Ca2＋,Cd2＋,Co2＋,Cu2＋,Hg2＋,K＋,Mg2＋,Na＋,Pb2＋,Zn2＋）did not interfere with its recognition.A linear relationship was observed between the fluorescence intensity of probe CDT and the concentration of Fe3＋in the range of 2×10-6-6×10-5 mol/L（R2=0.9965）.The detection limit of CDT for Fe3＋was 9.7×10-7 mol/L.The complex constant between CDT and Fe3＋was 3.3×104 L/mol.Meanwhile,the binding ratio of CDT and Fe3＋was found to be 1∶1.

关 键 词：噻唑 铁离子 荧光探针 识别 

分 类 号：O626.25[理学—有机化学]