黄芪及含黄芪经方在治疗肾病方面的药理作用及临床应用研究进展  

Research progress on pharmacological effects and clinical application of single Astragali Radix and classical formulae containing Astragali Radix in treatment of kidney disease

作　　者：杨柳 李爱平 张王宁 秦雪梅 YANG Liu;LI Ai-ping;ZHANG Wang-ning;QIN Xue-mei(Science and Technology Innovation Team of Shanxi Province,Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province,Taiyuan 030006,Chin)

机构地区：[1]地产中药功效物质研究与利用山西省重点实验室,山西省科技创新重点团队,山西太原030006

出　　处：《中草药》2018年第14期3419-3424,共6页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目：多效中药黄芪的定向药效化学成分研究(3157010673)

摘　　要：黄芪为临床常用中药,具有托毒生肌、补气升阳、利水消肿、益卫固表等功效。近年来黄芪及含黄芪经方在肾病方面的研究成为热点。查阅近5年国内外文献,针对黄芪及含黄芪经方的药理作用和临床应用方面的研究,进行系统地梳理与综述,旨为了解黄芪在不同复方中针对肾病的药效及其作用机制以及基于有效性合理评价黄芪资源提供理论基础,以促进黄芪治疗肾病的现代化研究进程。Astragali Radix with the functions of promoting pus discharge and tissue regeneration, tonifying qi and elevating yang, inducing diuresis to alleviate edema, and replenishing wei and consolidating exterior, has been widely used in clinics. The study of Astragali Radix and the classical formulae containing Astragali Radix in kidney disease is a hot topic in recent years. According to vast information from literatures in the last five years, this paper systematically reviewed the pharmacological activities and clinical applications of Astragali Radix and the classical formulae containing Astragali Radix, aiming at understanding the effect and mechanism of Astragalus Radix on kidney disease in different compatibilities. This study is expected to provide the theoretical basis for the reasonable evaluation of Astragalus Radix resources based on the effectiveness and promote the modernization of Astragali Radix in the field of kidney disease.

关 键 词：黄芪 含黄芪经方 肾脏疾病 药效物质基础 作用机制 

分 类 号：R285[医药卫生—中药学]