微波消解-ICP-OES法测定舒肝丸中朱砂的含量  

Determination of Zhusha(Cinnabar)in Shugan Pills(舒肝丸) by Microwave Digestion and ICP-OES

作　　者：刘永利 苏建 杜高峰 周亚楠 袁浩 冯丽 LIU Yong-li;SU Jian;DU Gao-feng;ZHOU Ya-nan;YUAN Hao;FENG Li(Hebei Institute for Drug Control,Shijiazhuang Hebei 050011,China)

机构地区：[1]河北省药品检验研究院,河北石家庄050011

出　　处：《中医药导报》2018年第15期59-60,81,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:建立舒肝丸中朱砂的ICP-OES含量测定方法。方法:采用硝酸-盐酸(3∶1)对舒肝丸进行微波消解,用ICP-OES法测定舒肝丸中朱砂的含量。结果:汞元素线性范围为0.05~40 mg/L,r=0.9999,大蜜丸回收率为101.9%,RSD%为1.6%(n=9),浓缩丸回收率为101.7%,RSD%为1.4%(n=9)。结论:该方法快速准确,操作简便,可用于舒肝丸中朱砂的含量控制。Objective： To establish a method for determination of Zhusha （cinnabar） in Shugan pills by ICP- OES. Methods： Microwave digestion with nitric acid-hydrochloric acid （3：1） was used in sample pretreatment, and ICP-OES was used to measure the contents of Zhusha （cinnabar） in Shugan Pills. Results： A good linear cor-relation of mercury was observed within the range of 0.05-40 mg/L （r=0.9999）, the recoveries of big-honeyed pill was 101.9%, RSD% was 1.6% （n=9） and concentrated pill was 101.7%, RSD% was 1.4% （n=9）. Conclusion： The method is feasible, accurate and stability, which can be used to control the content of Zhusha （cinnabar） in Shugan pills.

关 键 词：电感耦合等离子体原子发射光谱法 微波消解 舒肝丸 朱砂 

分 类 号：R284.1[医药卫生—中药学]