140例胎膜早破患者阴道液胎儿纤维连接蛋白与绒毛膜羊膜炎的临床分析  

Clinical Analysis of Vaginal Fluid FFN and Chorioamnionitis in 140 Patients with Premature Rupture of Membranes

作　　者：蒋红梅[1] Jiang Hong-mei(Jiamusi Central Hospital,Jiamusi,Heilongjiang,154002,China)

机构地区：[1]佳木斯市中心医院,黑龙江佳木斯154002

出　　处：《黑龙江医学》2018年第7期648-649,共2页Heilongjiang Medical Journal

摘　　要：目的对胎膜早破患者阴道液胎儿纤维连接蛋白(FFN)与绒毛膜羊膜炎之间的关系展开分析。方法选取佳木斯市中心医院收治的140例胎膜早破患者为观察组,另选取同期140例健康孕妇为对照组,检测两组孕妇的血清阴道液FFN及C-反应蛋白(CPR)。结束分娩后,还需对胎膜展开病理学检查。结果观察组患者的FFN阳性率及CPR阳性率均显著高于对照组,差异有统计学意义(P<0.05)。此外在观察组中,FFN阳性患者发生绒毛膜羊膜炎的概率相比于阴性患者明显升高,差异有统计学意义(P<0.05),且敏感性比较高。结论阴道液FFN与绒毛膜羊膜炎之间有着紧密联系,可将其作为预测胎膜早破患者是否发生绒毛膜羊膜炎的一项重要指标。Objective To analyze the relationship between FFN（ fetal fibronectin） and chorioamnionitis in patients with premature rupture of membranes. Methods 140 cases of premature rupture of membranes in the hospital were selected as the observation group,and 140 healthy pregnant women were selected as the control group at the same time. The serum vaginal fluid FFN and C-reactive protein（ CPR） of pregnant women were detected in two groups. After delivery,pathological examination of fetal membranes is necessary. Results The positive rate of FFN and the positive rate of CPR in the observation group were significantly higher than those in the control group（ P〈0. 05）. In addition,in the observation group,the probability of chorioamnionitis in FFN positive patients was significantly higher than that in negative patients（ P〈0. 05）,and the sensitivity was relatively high. Conclusion There is a close relationship between the vaginal FFN and chorioamnionitis,which can be used as an important indicator for predicting the incidence of chorionic amnionitis in patients with premature rupture of membranes.

关 键 词：胎膜早破 阴道液胎儿纤维连接蛋白 绒毛膜羊膜炎 

分 类 号：R714.433[医药卫生—妇产科学]