儿童单纯糠疹补锌治疗后疗效观察  

The observation of the clinical efficacy of zinc supplementation therapy in children patients with pityriasis alba

作　　者：唐显华 王茜 付小京 吴龙茂 徐霞[2] TANG Xian-hua;FANG Qian;FU Xiao-ring(Department of Dermatology,Ajfiliated Memorial Hospital of Southern Medical University,Panyu 511400,China;Permatology prevention and Treatment Institute of Guangzhou,Guangdong,Guangzhou 510000,China)

机构地区：[1]南方医科大学附属何贤纪念医院皮肤科,广东番禺511400 [2]广东省广州市皮肤病防治所,广东广州510000

出　　处：《吉林医学》2018年第8期1421-1423,共3页Jilin Medical Journal

基　　金：番禺区科技计划医疗卫生项目[项目编号:2015-Z03-37]

摘　　要：目的:探讨单纯糠疹的发病与微量元素锌的缺乏是否相关,并对单纯糠疹的患儿补锌后进行疗效观察。方法:选取128例单纯糠疹儿童和201名健康儿童进行微量元素锌测定,两组数据进行统计学分析。取24例单纯糠疹患儿,治疗组口服甘草锌颗粒加外用尿素软膏,对照组外用尿素软膏,1个月后复查两组皮疹和色度的改变。结果:单纯糠疹组患儿血锌低于健康儿童组,差异有统计学意义(P<0.05),补锌治疗组皮疹面积和色度的改善均优于对照组,差异有统计学意义(P<0.05)。结论:单纯糠疹的发病与锌的缺乏密切相关,及时补锌对疾病的治疗有重要意义。Objective To investigate whether zinc deficiency is involved in the pathogenesis of pityriasis alba,and assess the efficacy of zinc supplement for the children patients.Method 128 patients with pityriasis alba and 201 cases of healthy children were enrolled,the serum zinc levels were measured and analyzed statistically.24 patients were randomly divided into the treatment group and the control group,the treatment group received zinc supplement and topical urea cream treatment,the control group were topical treatment only.The lesions area and color change were calculated before and after one month treatment.Results The serum zinc levels of pityriasis alba group were significantly lower than the healthy group（P〈0.05）,the improvement of lesions area and color in the treatment group were superior to the control group（P〈0.05）.Conclusion Zinc deficiency is closely related to the development of pityriasis alba,zinc supplementation play an important role in treatment in the disease.

关 键 词：单纯糠疹 锌 皮疹面积 色度 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]