妊娠期高血压疾病孕妇血液流变学和血小板相关参数的变化分析  

Changes of hemorheological and platelet-related parameters in women with pregnancy-induced hypertension

作　　者：许艳蕾[1] 米梅艳[1] 张君娜[1] 强者[1] XU Yan-lei;MI Mei-yan;ZHANG Jun-na;QIANG Zhe(Department of Gynecology and Obstetrics,the Fourth Hospital of Shijiazhuang City,Hebei Province,Shijiazhuang 050000,Chin)

机构地区：[1]石家庄市第四医院妇产科,河北石家庄050000

出　　处：《中国当代医药》2018年第19期110-112,共3页China Modern Medicine

摘　　要：目的分析妊娠期高血压疾病孕妇血液流变学和血小板相关参数的变化。方法选取我院2015年1月2日~2016年2月10日妊娠期高血压疾病孕妇共90例,按照不同病情将其分为三组(重度子痫前期组、子痫前期组、妊娠高血压组,每组各30例),再选取同期正常晚孕孕妇30例作为正常晚孕组,分析各组孕妇的血液流变学和血小板相关参数。结果重度子痫前期组孕妇的红细胞聚集指数、血沉K值、低切还原黏度、全血低切黏度高于正常晚孕组、子痫前期组及妊娠期高血压组,差异有统计学意义(P<0.05);妊娠期高血压组红细胞聚集指数高于正常晚孕组及子痫前期组,差异有统计学意义(P<0.05);正常晚孕组血小板分布宽度、平均血小板体积低于重度子痫前期组、子痫前期组、妊娠期高血压组,差异有统计学意义(P<0.05);血小板计数低于妊娠期高血压组,差异有统计学意义(P<0.05)。结论妊娠期高血压疾病孕妇均存在血小板、血液流变学异常情况,而上述指标对妊娠期高血压疾病的防治和病情监测具有重要意义。Objective To analyze the changes of hemorheological and platelet-related parameters in women with pregnancy-induced hypertension.Methods A total of 90 pregnant women with gestational hypertension were selected and equally divided into three groups according to different disease conditions：severe preeclampsia group,preeclampsia group,pregnancy-induced hypertension group,30 cases in each group.Another group of 30 pregnant women with late pregnancy were classified into normal late pregnancy group during the same period.The cases were collected was from January 2,2015 to February 10,2016.The hemorheological and platelet-related parameters in pregnant women from different groups were analyzed.Results The erythrocyte aggregation index（EAI）,K value of erythrocyte sedimentation rate（ESR）,low-sheared reduction viscosity,and low-sheared viscosity of whole blood in the severe preeclampsia group were all higher than those in the other three groups with significant differences（P〈0.05）.The EAI in the pregnancy-induced hypertension group was higher than the normal late pregnancy group and the preeclampsia group with statistical significance（P〈0.05）.In the normal late pregnancy group,platelet distribution width and mean platelet volume were lower than those in the other three groups with statistical differences（P〈0.05）.The platelet count was lower in the normal late pregnancy group than that in the pregnancy-induced hypertension group with a significant difference（P〈0.05）.Conclusion There are abnormal platelet and hemorheological changes in women with pregnancy-induced hypertension.The indexes mentioned above are of great significance for the prevention and treatment of hypertensive disorders during pregnancy as well as its monitoring.

关 键 词：妊娠期高血压疾病 血液流变学 血小板相关参数 变化 

分 类 号：R714.246[医药卫生—妇产科学]