化瘀宁心汤对冠状动脉介入术后血脂及终点事件的影响  

Effect of Huayu Ningxin Decoction on Blood Lipid and Endpoint Events after Percutaneous Coronary Intervention

作　　者：李晓磊 段敏[2] 

机构地区：[1]河南省新密市第一人民医院心内一科,河南新密452370 [2]河南中医药大学第一附属医院心电图室,河南郑州450000

出　　处：《实用中医药杂志》2018年第8期888-889,共2页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察化瘀宁心汤对冠状动脉介入术后血脂及终点事件的影响。方法:94例随机分为观察组和对照组各47例,两组均用阿司匹林联合阿托伐他汀治疗,观察组加用化瘀宁心汤治疗。观察组术前和术后4周血脂水平、终点事件发生情况。结果:观察组治疗后TC、LDL-C、TG水平均低于治疗前和对照组(P<0.05),观察组终点事件发生率少于对照组(P<0.05),观察组冠状动脉再狭窄、心绞痛复发率低于对照组(P<0.05)。结论:化瘀宁心汤对冠状动脉介入术后血脂及终点事件有积极影响,能够降低血脂水平,减少终点恶性事件的发生,降低冠状动脉再狭窄、心绞痛复发率。Objective ： To observe the effect of Huayu Ningxin Decoction on blood lipid and endpoint events after percutaneous coronary intervention. Method： 94 cases were divided into 2 groups randomly, 47cases in observation group and 47 cases in control group. Both groups were treated with Aspirin combined with Atorvastatin and the observation group were treated with Huayu Ningxin Decoction in addition. The level of blood lipid before the operation and 4 weeks after the operation and the endpoint events occurrence were observed. Result： The level of TC, LDL-C and TG of the observation group after the treatment was lower than that before the treatment or that of the control group respectively （ P〈0.05 ） . The incidence of endpoint events of the observation group was superior to that of the control group （ P〈O.05 ） . The recurrence rate of coronary restcnosis or angina pectoris of the observation group was lower than that of the control group （ P〈0.05 ） . Conclusion： Huayu Ningxin Decoction has positive effect on blood lipid and endpoint events after percutaneous coronary intervention, which could decrease the level of blood lipid, reduce the incidence fo endpoint events and decrease the recurrence rate of coronary restenosis or angina pectoris.

关 键 词：冠状动脉介入术 化瘀宁心汤 血脂 终点事件 影响 

分 类 号：R256.224.33[医药卫生—中医内科学]