藏药四数獐牙菜的质量标准研究  

Study on the quality standard of Tibetan medicine Swertia tetraptera Maxim

作　　者：李琪[1] 莫家祺 王艺 邱洋 杜蕾蕾[2] 范刚[2] LI Qi;MO Jia-qi;WANG Yi;QIU Yang;DU Lei-lei;FAN Gang(School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan;School of Ethnic Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Siehuan)

机构地区：[1]成都中医药大学药学院,四川成都611137 [2]成都中医药大学民族医药学院,四川成都611137

出　　处：《中药与临床》2017年第5期15-17,26,共4页Pharmacy and Clinics of Chinese Materia Medica

基　　金：成都中医药大学科技发展基金(ZRQN1637)

摘　　要：目的:建立藏药四数獐牙菜药材的质量标准。方法:采用《中国药典》方法测定水分、总灰分、酸不溶性灰分和浸出物的含量,采用显微、薄层色谱法建立药材鉴别方法,采用HPLC法测定药材中龙胆苦苷的含量。结果:确定了四数獐牙菜药材的显微鉴别特征,建立了以龙胆苦苷为指标的薄层鉴别及含量测定方法。四数獐牙菜药材中龙胆苦苷的平均含量为3.11%。结论:该方法操作简便,准确可靠,重现性好,可用于藏药四数獐牙菜药材的质量控制。Objective： To establish the quality standard of Swertia tetraptera Maxim.（S.tetraptera）. Method： The moisture, total ash, acid-insoluble ash and alcohol-soluble extract were detected according to the procedures recorded in Chinese Pharmacopoeia（2015 edition）. The medicinal material was identified by microscopy and thin-layer chromatography（TLC） methods, and gentiopicroside was detected by HPLC method. Result： Microscopic characteristics of S. tetraptera were clarified. TLC and quantitative analysis method were established with gentiopicroside as index. The average content of gentiopicroside in S. tetraptera was 3.11%. Conclusion： The established method is simple to operate, having good stability and reproducibility, and can be used for quality control of S. tetraptera in the future.

关 键 词：藏药 四数獐牙菜 龙胆苦苷 质量标准 

分 类 号：R282[医药卫生—中药学]