管腔内对比度衰减梯度和改良校正的管腔内对比度衰减梯度分级诊断冠状动脉狭窄  

Transluminal contrast attenuation gradient and modified transluminal contrast attenuation gradient corrected coronary opacification in grading diagnosis of coronary artery stenosis

作　　者：阚晓婧[1] 葛英辉[1] 刘霄静 张继良[1] 谢瑞刚[1] 王鹏铭 KAN Xiaojing;GE Yinghui;LIU Xiaojing;ZHANG Jiliang;XIE Ruigang;WANG Pengming(Department of Radiology,Henan Provincial People’s Hospital,Henan University People’s Hospital,Zhengzhou 450003,Chin)

机构地区：[1]河南省人民医院河南大学人民医院影像科，河南 郑州 450003

出　　处：《中国医学影像技术》2018年第8期1182-1186,共5页Chinese Journal of Medical Imaging Technology

基　　金：河南省医学科技攻关项目(201702160);河南省科技厅立项(172102310520)

摘　　要：目的观察管腔内对比度衰减梯度(TAG)和改良校正的管腔内对比度衰减梯度(MTAG-CCO)分级诊断冠状动脉狭窄的价值。方法回顾性分析133例(302支狭窄血管)冠状动脉狭窄患者(狭窄组)和53例(130支血管)无冠状动脉狭窄患者(对照组)的冠状动脉CTA(CCTA)资料。对狭窄组行冠状动脉造影,并将其分为5个亚组:1级亚组,狭窄程度<25%;2级亚组,25%≤狭窄程度<49%;3级亚组,49%≤狭窄程度<69%;4级亚组,69%≤狭窄程度<99%;5级亚组,狭窄程度≥99%。测量并比较组间及亚组间TAG、MTAG-CCO值。结果狭窄组TAG值[-(18.20±7.42)HU/10mm]低于对照组[-(12.39±4.40)HU/10mm;Z=9 389.00,P<0.001],MTAG-CCO值[-(0.027±0.011)/10mm]亦低于对照组[—(0.014±0.005)/10mm;Z=4 555.50,P<0.001]。狭窄组各亚组TAG及MTAG-CCO值与对照组比较差异均有统计学意义(P均<0.05)。1级、2级亚组TAG值高于4级、5级亚组(P均<0.05)。1级、2级亚组MTAGCCO值高于3级、4级、5级亚组,3级亚组MTAG-CCO值高于5级亚组(P均<0.05),其余亚组间TAG及MTAG-CCO值差异均无统计学意义(P均>0.05)。结论 TAG及MTAG-CCO均有助于分级诊断冠状动脉狭窄。Objective To investigate the value of transluminal contrast attenuation gradient（TAG）and modified TAGcorrected coronary opacification（MTAG-CCO）in the grading of coronary artery stenosis.Methods CCTA data of 133 patients（302 stenosis vessels）with coronary artery stenosis（stenosis group）and 53 patients（130 vessels）without coronary artery stenosis（control group）were analyzed retrospectively.Vessels in stenosis group were divided into 5 subgroups：Subgroup 1,diameter stenosis（DS）〈25%;subgroup 2,25% ≤DS〈49%;subgroup 3,49% ≤DS〈69%;subgroup 4,69% ≤DS〈99%;subgroup 5,DS≥99%.TAG and MTAG-CCO values were measured and compared,respectively.Results TAG of stenosis group（-[18.20±7.42]HU/10 mm）was lower than that of control group（-[12.39±4.40]HU/10 mm;Z=9 389.00,P〈0.001）,and MTAG-CCO of stenosis group（-[0.027±0.011]/10 mm）was lower than that of control group（—[0.014±0.005]/10 mm;Z=4 555.50,P〈0.001）.TAG and MTAGCCO values in subgroups of stenosis group were significantly different compared with those in control group（all P〈0.05）.TAG value of subgroup 1 and 2 was higher than that of subgroup 4 and 5（all P〈0.05）.MTAG-CCO value of subgroup 1 and 2 was higher than that of subgroup 3,4 and 5,while of subgroup 3 was higher than that of subgroup 5（all P〈0.05）.However,there was no significant difference of TAG nor MTAG-CCO values among other subgroups（all P〉0.05）.Conclusion TAG and MTAG-CCO are helpful to grading of coronary artery stenosis.

关 键 词：冠状动脉狭窄 体层摄影术 X线计算机 

分 类 号：R543.3[医药卫生—心血管疾病] R816.2[医药卫生—内科学]