综合性康复治疗对老年头颈部肿瘤患者放疗后生活质量的影响  

Effect of comprehensive rehabilitation treatment on quality of life in elderly patients with head and neck cancer after radiotherapy

作　　者：王剑锋[1] 宗敏茹[2] 刘大海[3] WANG Jian-Feng;ZONG Min-Ru;LIU Da-Hai(depar tment of Radiotherap;Department of Rehabilitation Medicine;Department of Lymphatic Vascular Surgery,China-Japan Union Hospital of Jilin University,Changchun 130033,China)

机构地区：[1]吉林大学中日联谊医院放疗科,长春130033 [2]吉林大学中日联谊医院康复科,长春130033 [3]吉林大学中日联谊医院淋巴血管外科,长春130033

出　　处：《中华老年多器官疾病杂志》2018年第6期416-419,共4页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：吉林省自然科学基金(20160101344JC)~~

摘　　要：目的探讨综合性康复治疗对老年头颈部肿瘤患者放疗后情绪、营养状况和生活质量的影响。方法选取2015年6月至2017年6月在吉林大学中日联谊医院放疗科完成放疗的老年头颈部肿瘤患者62例,采用随机数字表法分为康复组(n=31)和对照组(n=31)。对照组接受常规健康咨询和随访;康复组在此基础上接受包括心理疏导、体力锻炼、吞咽训练和营养干预的综合性康复治疗。在放疗结束和放疗后6个月时,2组患者均接受老年抑郁量表(GDS)、微型营养评估简表(MNA-SF)和生活质量调查表(QLQ-C 30)评价。采用SPSS 19.0统计软件进行统计分析,计量资料以均数±标准差表示,组间比较采用t检验,计数资料以例数(百分率)表示,组间比较采用χ~2检验。结果放疗结束时,2组患者GDS、MNA-SF、QLQ-C 30评分差异均无统计学意义。放疗后6个月时,康复组的GDS评分[(7.35±1.75)vs(10.20±1.94)]、MNA-SF评分[(10.85±3.23)vs(9.56±4.21)]和QLQ-C 30评分[(57.84±9.57)vs(49.73±10.01)]均明显优于对照组(P<0.05);而对照组MNA-SF评分较放疗结束时明显改善[(9.56±4.21)vs(8.24±4.05),P<0.05]。结论综合性康复治疗可更有效改善老年头颈部患者放疗后的抑郁状态和营养状况,提高患者的生活质量。Objective To determine the effect of comprehensive rehabilitation treatment on emotion,nutritional status,and quality of life in elderly patients with head and neck cancer after radiotherapy. Methods A total of 62 elderly patients with head and neck cancer completing radiotherapy in our hospital from June 2015 to June 2017 were enrolled in this study. They were randomly divided into rehabilitation group（ n = 31） and control group（ n = 31）. The patients from the both groups were given routine healthy counseling and follow-up,while those of the former group were additionally provided with comprehensive rehabilitation treatment,including psychological counseling,physical exercise,swallowing training and nutrition intervention. They were assessed with geriatric depression scale（ GDS）,mini-nutritional assessment short-form（ MNA-SF）,quality of life questionnaire-core 30（ QLQ-C 30） immediately after radiotherapy and 6 months after radiotherapy. SPSS statistics 19. 0 was used for data analysis. The measurement data were expressed as mean ± standard deviation,and Student＇s t test was employed for the comparison between groups. Results There were no statistical differences in scores of GDS,MNA-SF and QLQ-C 30 immediately after radiotherapy. At 6 months after radiotherapy,the scores of GDS[（ 7. 35 ± 1. 75） vs（ 10. 20 ± 1. 94） ],MNA-SF [（ 10. 85 ± 3. 23） vs（ 9. 56 ± 4. 21） ] and QLQ-C 30 [（ 57. 84 ± 9. 57） vs（ 49. 73 ± 10. 01） ] in the rehabilitation group were all significantly better than those in control group（ P 0. 05）. The score of MNA-SF in the control group was significantly better than that immediately after radiotherapy [（ 9. 56 ± 4. 21） vs（ 8. 24 ± 4. 05）,P 0. 05]. Conclusion Comprehensive rehabilitation treatment can more significantly improve the depressive status,nutritional status and quality of life in the elderly patients with head and neck cancer after radiotherapy.

关 键 词：头颈部肿瘤 老年 康复 生活质量 

分 类 号：R493[医药卫生—康复医学] R592[医药卫生—临床医学]