Correlations between the Maximum Standard Uptake Value of Positron Emission Tomography/Computed Tomography and Laboratory Parameters before and after Treatment in Patients with Lymphoma  

作　　者：Edip Ucar Hulya Yalcin Edip Ucar;Hulya Yalcin;Gamze Hande Kavvasoglu;Gul Ilhan(Department of Internal Medicine, Tayfur Ata Sokmen Medical School, Mustafa Kemal University, Antioch, Hatay 31100, Turkey;Department of Nuclear Medicinel Ta~ur Ata Sokmen Medical School, Mustafa Kemal University, Antioch, HataY 31100, Turkey)

机构地区：[1]Gamze Hande Kavvasoglu1,Gul Ilhan1 1Department of Internal Medicine,Tayfur Ata Sokmen Medical School,Mustafa Kemal University,Antioch,Hatay 31100,Turkey [2]Department of Nuclear Medicine,Tayfur Ata Sokmen Medical School,Mustafa Kemal University,Antioch,Hatay 31100,Turkey

出　　处：《Chinese Medical Journal》2018年第15期1776-1779,共4页中华医学杂志（英文版）

摘　　要：Background： After the first examination of patients with lymphoma diagnosis, important laboratory tests such as complete blood count; albumin, kidney and liver function tests; uric acid; 132-microglobulin; C-reactive protein （CRP）; erythrocyte sedimentation rate （ESR）; and lactate dehydrogenase （LDH） examinations are recommended. In this study, our aim was to find the relationship between laboratory parameters and the maximum standard uptake value （SUVmax） of positron emission tomography/computed tomography （PET/CT） in patients with lymphoma at the diagnosis and after treatment. Methods： Thirty-tbur lymphoma patients treated at Mustafa Kemal University Internal Medicine Clinic between 2014 and 2017 were included in this retrospective study. Results ofCRP, ESR, LDH, albumin, and white blood cell （WBC） count were recorded betbre each PET scan test, and each parameter was analyzed for correlation with SUV measurements. Results： Spearman＇s correlation test showed that the after-treatment SUV values were significantly correlated with the alter-treatment LDH, ESR, and CRP values （for LDH, ESR, and CRP, R2： 0.453, 0.426, and 0.351; P = 0.007, 0.012, and 0.042, respectively）. On the other hand, albumin and WBC count did not show a significant correlation with the after-treatment SUVmax values （all P 〉 0.05）. Conclusions： CRP, ESR, and LDH values may also be good predictors in patients for whom PET/CT imaging cannot be performed.Background： After the first examination of patients with lymphoma diagnosis, important laboratory tests such as complete blood count; albumin, kidney and liver function tests; uric acid; 132-microglobulin; C-reactive protein （CRP）; erythrocyte sedimentation rate （ESR）; and lactate dehydrogenase （LDH） examinations are recommended. In this study, our aim was to find the relationship between laboratory parameters and the maximum standard uptake value （SUVmax） of positron emission tomography/computed tomography （PET/CT） in patients with lymphoma at the diagnosis and after treatment. Methods： Thirty-tbur lymphoma patients treated at Mustafa Kemal University Internal Medicine Clinic between 2014 and 2017 were included in this retrospective study. Results ofCRP, ESR, LDH, albumin, and white blood cell （WBC） count were recorded betbre each PET scan test, and each parameter was analyzed for correlation with SUV measurements. Results： Spearman＇s correlation test showed that the after-treatment SUV values were significantly correlated with the alter-treatment LDH, ESR, and CRP values （for LDH, ESR, and CRP, R2： 0.453, 0.426, and 0.351; P = 0.007, 0.012, and 0.042, respectively）. On the other hand, albumin and WBC count did not show a significant correlation with the after-treatment SUVmax values （all P 〉 0.05）. Conclusions： CRP, ESR, and LDH values may also be good predictors in patients for whom PET/CT imaging cannot be performed.

关 键 词：ALBUMIN C-reactive Protein： Erythrocyte Sedimentation Rate： Lactate Dehydrogenase LYMPHOMA Maximum StandardUptake Value： Positron Emission Tomography/Computed Tomography White Blood Cell Count 

分 类 号：O572.2[理学—粒子物理与原子核物理] U418.4[理学—物理]