Selective aerobic oxidation of p-cresol with co-catalysts between metalloporphyrins and metal salts  

作　　者：Yuanbin She Yao Fan Lei Zhang Ying Xu Min Yu Haiyan Fu 

机构地区：[1]State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology [2]The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences, South Central University for Nationalities

出　　处：《Chinese Journal of Chemical Engineering》2018年第7期1493-1498,共6页中国化学工程学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China(21776259,21776321,21706233,21576297,21476270)

摘　　要：A green and efficient method for the selective aerobic oxidation of p-cresol to p-hydroxybenzaldehyde catalyzed by co-catalysts between metalloporphyrins and metal salts was investigated and developed. The relationship between the synergistic catalytic effects and the composition as well as amount of co-catalysts was investigated. Moreover, the influence of different reaction conditions was studied in details. A high p-cresol conversion （〉99%） and p-hydroxybenzaldehyde selectivity （83%） were obtained using only 1.125 × 10- 5 mol T（p-CH3O）PPFe111Cl-Co（OAc）2 used under mild, optimized reaction conditions. A possible mechanism for the reaction was also proposed. This work would be meaningful and instructive for the further researches and applications of co-catalyst system on oxidation of cresols and could give some enlightenment on the selectively catalytic oxidation of the side-chain alkyls of aromatics.A green and efficient method for the selective aerobic oxidation of p-cresol to p-hydroxybenzaldehyde catalyzed by co-catalysts between metalloporphyrins and metal salts was investigated and developed. The relationship between the synergistic catalytic effects and the composition as well as amount of co-catalysts was investigated. Moreover, the influence of different reaction conditions was studied in details. A high p-cresol conversion(N 99%) and p-hydroxybenzaldehyde selectivity(83%) were obtained using only 1.125 × 10^(-5) mol T(p-CH_3 O)PPFe^(III)Cl-Co(OAc)_2 used under mild, optimized reaction conditions. A possible mechanism for the reaction was also proposed. This work would be meaningful and instructive for the further researches and applications of co-catalyst system on oxidation of cresols and could give some enlightenment on the selectively catalytic oxidation of the side-chain alkyls of aromatics.

关 键 词：AEROBIC Oxidation Selectivity CO-CATALYST METALLOPORPHYRIN CRESOLS 

分 类 号：O621.251[理学—有机化学]