咪唑离子液体作为流动相添加剂的整体柱离子对色谱快速分析哌啶阳离子  

Rapid Analysis of Piperidinium Cations by Monolithic Column Ion Pair Chromatography Using Imidazolium Ionic Liquids as Mobile Phase Additives

作　　者：张雪[1] 于泓[1] 马亚杰[1] 黄旭[1] 刘泽坤 ZHANG Xue;YU Hong;MA Ya-jie;HUANG Xu;LIU Ze-kun(College of Chemistry and Chemical Engineering,Harbin Normal University,Harbin 150025)

机构地区：[1]哈尔滨师范大学化学化工学院,黑龙江哈尔滨150025

出　　处：《分析科学学报》2018年第4期501-506,共6页Journal of Analytical Science

基　　金：黑龙江省自然科学基金(No.B201307);哈尔滨师范大学创新团队和大学生实践创新基金

摘　　要：以咪唑离子液体作为流动相添加剂,建立了哌啶离子液体阳离子的整体柱离子对色谱-间接紫外检测分析方法。系统研究了流动相、流速等因素对哌啶阳离子分离测定的影响情况。流动相中的咪唑离子液体不仅起到了背景紫外吸收剂的作用,还改善了阳离子的分离效果。用0.5mmol/L 1-乙基-3-甲基咪唑四氟硼酸盐-0.1mmol/L庚烷磺酸盐水溶液(pH=4.5)/甲醇(90/10,V/V)作为流动相,流速3.0mL/min,检测波长210nm,N-甲基-N-乙基、N-甲基-N-丙基和N-甲基-N-丁基哌啶阳离子在3.0min之内实现基线分离。3种哌啶阳离子的检出限分别为0.13、0.34和0.42mg/L。该方法测定实验室合成的哌啶离子液体样品的加标回收率范围为94%~98%。An analytical method of ion pair chromatography with indirect UV detection using imidazolium ionic liquids as mobile phase additives has been developed for the separation and detection of piperidinium ionic liquid cations.The effects of the mobile phases and flow rate on the determination of piperidinium cations were investigated.Imidazolium ionic liquid in the mobile phase not only played a role in the background UV absorption reagent,but also improved the separation of the cations.The target compounds of N-methyl-N-ethyl-piperidinium cation,N-methyl-N-propyl-piperidinium cation and N-methyl-N-butyl-piperidinium cation were effectively separated within 3.0 min under the conditions of 0.5 mmol/L 1-ethyl-3-methyl-imidazolium tetrafluoroborate-0.1 mmol/L 1-heptanesulfonic sodium aqueous solution（pH=4.5）/methanol（90/10,V/V）as mobile phase,the flow rate of 3.0 mL/min and detection wavelength of 210 nm.The limits of detection for the three piperidinium cations were 0.13,0.34 and 0.42 mg/L,respectively.The method was used to the determination of laboratory synthetic piperidinium ionic liquid samples with excellent separation performance,and the spiked recoveries were in the range of 94%-98%.

关 键 词：离子液体 哌啶阳离子 整体柱 离子对色谱 间接紫外检测 

分 类 号：O657.7[理学—分析化学]