机构地区:[1]天津医科大学研究生学院,300070 [2]天津市天津医院微创脊柱外科,300211
出 处:《中华骨科杂志》2018年第15期935-942,共8页Chinese Journal of Orthopaedics
基 金:国家自然科学基金面上项目(31670983,81272046,31500781);天津市自然科学基金(15JCYBJC25300)
摘 要:目的 探讨显微镜和可动式椎间盘镜(mobile microendoscopic discectomy,MMED)下行颈椎前路减压的可行性,并对比其临床疗效.方法 回顾性分析2015年5月至2017年2月采用显微镜或MMED辅助下行颈椎前路减压治疗30例脊髓型颈椎病患者资料,均采用常规颈前横切口,安置椎间撑开器,镜下减压后在直视下行融合固定.显微镜组15例,男4例,女11例;年龄32~71岁,平均(54.00±11.10)岁;前路颈椎间盘切除融合术(anterior cervical discectomy and fusion,ACDF)12例,前路颈椎次全切除融合术(anterior cervical corpectomy and fusion,ACCF)3例.MMED组15例,男9例,女6例;年龄39~73岁,平均(59.60±11.10)岁;ACDF 13例,ACCF 2例.记录手术时间和术中出血量;两组患者术后随访时间6~18个月,采用日本骨科协会(Japanese Orthopaedic Association,JOA)评分并计算神经功能改善率评估临床疗效;采用颈椎功能障碍指数(neck disabilitv index,NDI)评定颈椎功能.结果 两组患者均在镜下顺利完成减压,且未有神经症状加重.显微镜术中需分别调整镜头和器械方向,MMED镜头可随器械同步移动,更容易显露椎体后缘和椎管左、右侧.显微镜组手术时间90~180 min,平均(124.67±36.42)min;MMED组手术时间80~130 min,平均(110.00±15.12) min;两组差异无统计学意义(t=1.440,P=0.161).显微镜组术中出血量20~200 ml,平均(66.00±49.11)ml;MMED组术中出血30~150 ml,平均(60.00±35.25) ml;两组差异无统计学意义(t=0.384,P=0.704).显微镜组JOA评分由术前(8.67±3.20)分改善至末次随访时(15.93±1.53)分,两者比较差异有统计学意义(t=8.687,P=0.000);神经功能改善率分级,优12例、良3例,优良率100%;NDI自术前18.00%±9.75%降至末次随访时5.93%±2.58%,两者比较差异有统计学意义(t=5.137,P=0.000).MMED组JOA评分自术前(8.87±3.11)分改善至末次随访时(15.53±1.69)分,两者比较差异有统�Objective To explore the feasibility of anterior cervical decompression assisted with the microscope and mobile microendoscopic discectomy (MMED),and to compare their clinical efficacy.Methods From May 2015 to February 2017,thirty patients with cervical spondylotic myelopathy (CSM) underwent anterior cervical decompression assisted with microscope or MMED.Among them,conventional transverse anterior cervical incisions were used,and intervertebral distractors were placed in order to complete the decompression,then the fusion and fixation procedure were conducted under direct vision,and the operative time and intraoperative blood loss were recorded.Of 30 cases,15 cases were in microscope cohort (anterior cervical discectomy and fusion,ACDF 12 cases;anterior cervical corpectomy and fusion,ACCF 3 cases),including 4 males and 11 females with a mean age of 54.00±11.10 years (range,32-71 years).Another 15 cases were in MMED cohort (ACDF 13 cases,ACCF 2 cases),including 9 males and 6 females with a mean age of 59.60± 11.10 years (range,39-73 years).Neurological and cervical function were evaluated before surgery and at the follow-up according to the Japanese Orthopaedic Association (JOA) and the neck disability index (NDI) scores,and the neurologic improvement grade (NIG) was used to evaluate the neurological function.Results Both the microscope and MMED cohort underwent decompression successfully,and the visual field was clear.No neurological symptoms became worse.For the microscope,its lens and the instrument had to be adjusted separately,whereas MMED lens could move synchronously with the instrument.It was easier for MMED to reveal the posterior edge of the vertebral body and the left and right side of the spinal canal.The operation time of the microscope cohort was 90-180 min,with an average of 124.67±36.42 min;the M MED cohort was operated for 80-130 min with an average of 110.00± 15.12 min,and there was no significant difference between the two cohorts (t=1.440,P=0.161).Th
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