冠心病患者植入药物洗脱支架的远期预后及相关危险因素分析  

Long-term prognosis and related risk factors of implanted drug-eluting stent in patients with coronary heart disease

作　　者：焦方晓[1] 马巧红[1] 张彦宁[1] 陈大鹏 JIAO Fangxiao;MA Qiaohong;ZHANG Yanning;CHEN Dapeng(Department of Cardiovascalar medcine,The People ＇s Hospital of Guyuan,Guyuan 756000,China;Department of Cardiovascalar medcine,General Hospital of Ningxia Medical University,Yin-chuan 750004,China)

机构地区：[1]宁夏固原市人民医院心血管内科,宁夏固原756000 [2]宁夏医科大学总医院心脏中心,宁夏银川750004

出　　处：《宁夏医学杂志》2018年第7期611-614,共4页Ningxia Medical Journal

摘　　要：目的分析冠心病患者植入药物洗脱支架的远期预后情况及其相关危险因素。方法收集100例使用植入药物洗脱支架治疗的患者作为研究对象。根据患者是否发生不良反应以及植入情况将其分为2组,即非MACE事件组和MACE事件组。收集患者在治疗后的临床资料,并通过电话随访、上门服务、到院复诊等方法对其预后进行分析,收集其在植入药物洗脱支架后的危险因素。结果本次研究中所有患者均成功随访,时间为12个月。随访期间死亡率6%。不良事件发生率15%,脑血管疾病、心肌梗死和死亡发生率10%,支架内部再狭窄发生率4%,有1例患者术后出现晚期支架内血栓形成,占比1%。对相关危险因素进行分析后显示,多支病变、年龄较高、心率快、LVEF低是植入药物洗脱支架后出现不良事件的主要危险因素(P<0.05)。结论冠心病患者在植入药物洗脱支架后,其远期预后情况和多支病变、高龄等诸多因素有关,在临床治疗时需对这些危险因素进行着重关注。Objective To analyze the long-term prognosis of patients with coronary heart disease（ CHD） and the related risk factors. Methods 100 patients treated with implanted drug-eluting stent were enrolled in this study. The clinical data were collected and the prognosis was analyzed by telephone follow-up,door-to-door service and hospital referral. The risk factors were collected after implantation of drug-eluting stents. Results All patients in this study were followed up for a period of 12 months. Mortality rate during follow-up was 6%. The incidence of adverse events was 15%,the incidence of cerebrovascular disease,myocardial infarction and death was 10%,and the incidence of restenosis was 4% in the stent. One patient had late stent thrombosis after operation,accounting for 1%. Analysis of the relevant risk factors showed that multivessel disease,age,fast heart rate,LVEF low were the main risk factors of adverse events after the implanted drug-eluting stent（ P〈0. 05）. Conclusion The long-term prognosis of patients with coronary heart disease after implanted drug-eluting stent is related to many factors,such as multi-vessel disease and age. These risk factors need to be drew attention in clinical treatment.

关 键 词：冠心病患者 植入药物洗脱支架 远期预后 相关危险因素 

分 类 号：R259[医药卫生—中西医结合]