不同产地炒牛蒡子饮片中24种无机元素的ICP-MS分析  

ICP-MS analysis of 24 kinds of inorganic elements in processed Fructus Arctii from different habitats

作　　者：胡静[1] 庄延双[1] 杨冰[1] 朱晓钗 朱星宇[1] 蔡宝昌[1,2,3] 秦昆明 HU Jing;ZHUANG Yan-shuang;YANG Bing;ZHU Xiao-chai;ZHU Xing-yu;CAI Bao-chang;QIN Kun-ming(Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing,Nanjing University of Chinese Medicine,Nanjing 210023,China;Nanjing Haiyuan Prepared Slices of Chinese Crude Drugs Co.Ltd,Nanjing 210061,China;Nanjing Haichang Chinese Medicine Corporation,Nanjing 210061,China;Huaihai Institute of Technology,Lianyungang 222000,China)

机构地区：[1]南京中医药大学国家教育部中药炮制规范化及标准化工程研究中心,江苏南京210023 [2]南京海源中药饮片有限公司,江苏南京210061 [3]南京海昌中药集团有限公司,江苏南京210061 [4]淮海工学院,江苏连云港222000

出　　处：《时珍国医国药》2018年第4期809-813,共5页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金青年基金项目(81603297);国家自然科学基金(81573603);江苏省普通高校研究生科研创新计划项目(KYZZ16_0413);江苏省六大人才高峰资助项目(SWYY-108);江苏省333人才工程项目(2016-3-0277)

摘　　要：目的测定不同产地炒牛蒡子饮片中无机元素的含量。方法样品经微波消解后,采用ICP-MS法测定无机元素的含量,用SPSS 23.0对数据进行主成分分析、相关性分析。结果检测了炒牛蒡子饮片24种元素,元素之间有一定的相关性,K,P,Mg,Al,Na,Fe的含量较高,重金属及有害元素的含量在限量标准之内;主成分分析选出2个主因子,显示Al,V,Si,Ti,Fe,Mn,Ni,Cr,Co,Pb,Li,P,Mg,Mo,Sr,Cd是炒牛蒡子饮片的特征无机元素。结论该研究为炒牛蒡子饮片的质量控制及安全性评价提供了依据。Objective To determine the contents of the inorganic elements in processed Fructus Arctii from different habitats.Methods The sample solutions were analyzed by ICP-MS after microwave digestion. The data of principal components,correlations were analyzed with the SPSS 23. 0 software. Results Twenty four inorganic elements in processed Fructus Arctii were determined. There were some correlations among the inorganic elements in processed Fructus Arctii. The contents of K,P,Mg,Al,Na and Fe were abundant. The content of heavy metals and harmful elements are within the limits. Two main factors were selected PCA,which showed that Al,V,Si,Ti,Fe,Mn,Ni,Cr,Co,Pb,Li,P,Mg,Mo,Sr and Cd may be the characteristic elements in processed Fructus Arctii. Conclusion This experiment provides the evidence for the quality control and safety evaluation of processed Fructus Arctii.

关 键 词：炒牛蒡子 无机元素 电感耦合等离子体质谱(ICP-MS) 

分 类 号：R284.1[医药卫生—中药学]