卷柏属植物化学成分及其药理作用研究进展  

Advances in Research on Chemical Constituents and Pharmacological Activities of Genus Selaginella

作　　者：金旭东 卢轩[1] 王惠国[1] 史丽颖[1] 于大永[1,2] 冯宝民 JIN Xu-dong;LU Xuan;WANG Hui-guo;SHI Li-ying;YU Da-yog;FENG Bao-min(School of Life Science and Technology,Dalian University,Dalian 116622,China;Key Laboratory of Bio-marker High Throughput Screening and Target Translation of Breast and Gastrointestinal Tumor,Dalian 116001,China)

机构地区：[1]大连大学生命科学与技术学院,辽宁大连116622 [2]乳腺及消化肿瘤分子标志物高通量筛选及靶向药物转化重点实验室,辽宁大连116001

出　　处：《时珍国医国药》2018年第4期959-963,共5页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(31270398;31540006);辽宁省"百千万人才工程"人选项目择优资助项目(2013921008)

摘　　要：目的综述卷柏属植物化学成分和药理作用的研究进展。方法收集整理相关文献56篇,从卷柏属植物的化学成分和药理作用等方面对目前研究进行归纳和总结。结果卷柏属植物主要含有黄酮类、炔酚类、苯丙素类等多种化学成分其药理作用主要集中在抗肿瘤、抗病毒、抗菌、抗氧化、抗衰老和降血糖等方面。结论为卷柏属植物药用开发提供参考。Objective To summarize the progress of the chemical characters and pharmacological effects of Selaginella Genus.Methods 56 literatures were collected and summarized,and the current research was summarized from the aspects of chemical composition and pharmacological action of Selaginella. Results Selaginella mainly contains flavonoids,selaginellin,phenanthrolines and other chemical composition,the pharmacological activities are mainly concentrated in antitumor,antiviral,antibacterial,antioxidant,anti-aging,hypoglycemic and other effects. Conclusion This review provides a useful reference for the pharmaceutical application of Selaginella.

关 键 词：卷柏属 化学成分 药理活性 

分 类 号：R282.71[医药卫生—中药学]