双氯芬酸钠利多卡因在驻香港部队官兵肛门疾病术后镇痛中的应用效果研究  

Clinical effect of diclofenac sodium and lidocaine hydrochloride injection in postoperative analgesia of anus disease of officers and soldiers in Hong Kong troops

作　　者：鲁妍 聂晨阳[1] 刘峰 王悦 李程远 谢志勇 穆春来 马勇 张斌 李森 无 LU Yan;NIE Chenyang;LIU Feng;WANG Yue;LI Chengyuan;XIE Zhiyong;MU Chunlai;MA Yong;ZHANG Bin;LI Sen(Hong Kong Garrison Hospital of PLA,Hong Kong 999077,China;Air Force Institute of Aerospace Medicine Affiliated Hospital;Guangzhou General Hospital of PLA;The 59th Central Hospital of PLA;Lanzhou General Hospital of PLA)

机构地区：[1]解放军驻香港部队医院,中国香港999077 [2]空军航空医学研究所附属医院 [3]解放军广州总医院 [4]解放军兰州总医院 [5]解放军59中心医院

出　　处：《西北国防医学杂志》2018年第7期444-447,共4页Medical Journal of National Defending Forces in Northwest China

摘　　要：目的:探讨驻香港部队官兵肛门疾病术后使用双氯芬酸钠利多卡因镇痛的临床疗效。方法:选取2012-01-01~2017-12-31我院治疗的肛门疾病术后患者136例,随机分为2组:观察组76例,采用双氯芬酸钠利多卡因注射液2ml肌肉注射镇痛;对照组60例,采用盐酸哌替啶100mg+枸橼酸芬太尼0.3g,8ml/h持续静脉泵入6~8h镇痛。比较2组疗效及不良反应发生率。结果:观察组术后24h切口处疼痛均可耐受。对照组术后12h出现切口处疼痛,36例疼痛难忍,给予加强治疗。观察组显效率和总有效率均明显高于对照组(P<0.01)。观察组不良反应发生率明显低于对照组(P<0.01)。结论:双氯芬酸钠利多卡因注射液在肛门疾病术后镇痛中的效果优于盐酸哌替啶+枸橼酸芬太尼,且单一用药安全性高、疗效可靠,值得临床推广应用。Objective：To investigate the clinical analgesic effect of diclofenac sodium and lidocaine in postperative analgesia of anus diseases in Hong Kong troops.Methods：A total of136 patients with anus disease after operation who were treated in our hospital from January2012 to December 2017 were selected,and were randomly divided into two groups：76 cases in the observation group,who were treated with diclofenac sodium and lidocaine hydrochloride injection 2 ml muscle injection,and 60 cases in the control group,who were treated with piperidine hydrochloride 100 mg plus citric acid fentanyl 0.3 g,8 ml/h pump for 6-8 hours.The clinical effect and incidence of adverse reactions were compared.Results：Observation group had mild but no severe incision pain in 24 hours after operation.Control group had mild incision pain in 12 hours after operation,and 36 patients suffered from severe pain.The efficiency rate and total effective rate in observation group were higher than those in control group（P〈0.01）.The incidence of adverse reactions in observation group were lower than that in control group（P〈0.01）.Conclusion：The analgesic effect of intramuscular injection of diclofenac sodium and lidocaine hydrochloride after the surgery of anus disease is better than that of piperidine hydrochloride and fentanyl citrate,the single medication has high satisfactory and reliable curative effect,it is worthy of clinical promotion and application.

关 键 词：肛门疾病术后 双氯芬酸钠利多卡因注射液 镇痛效果 

分 类 号：R547.8[医药卫生—心血管疾病]