蒲地蓝消炎口服液治疗小儿咽结膜热的疗效及依从性观察  

Efficacy and Compliance of Pudilan Xiaoyan Oral Liquid in the Treatment of Children with PharyngoConjunctival Fever

作　　者：吕广秀[1] 周娟 曹勇 Lyv Guangxiu;Zhou Juan;Cao Yong(85th Hospital of People＇s Liberation Army,Shanghai 200052,China;Shanghai Hongkang Hospital,Shanghai 200333,China)

机构地区：[1]解放军第八五医院,上海200052 [2]上海宏康医院,上海200333

出　　处：《儿科药学杂志》2018年第8期23-25,共3页Journal of Pediatric Pharmacy

摘　　要：目的:分析蒲地蓝消炎口服液治疗小儿咽结膜热的疗效与依从性。方法:将257例咽结膜热的患儿随机分为治疗组与对照组,两组患儿均给予退热等对症处理。治疗组予以蒲地蓝消炎口服液每次5~10 m L口服,3次/天;对照组予以更昔洛韦注射液5 mg/(kg·d)静脉滴注,两组患儿均5 d为1个疗程。结果:治疗组总有效率92.6%(112/121),对照组总有效率93.4%(127/136),两组比较差异无统计学意义(P>0.05),治疗组的治疗依从性比对照组高(P<0.01)。结论:蒲地蓝消炎口服液治疗小儿咽结膜热疗效肯定,与更昔洛韦相比较疗效相当,但蒲地蓝消炎口服液服药依从性好,小儿与家长更易接受,值得临床推广应用。Objective： To analyze the efficacy and compliance of Pudilan Xiaoyan oral liquid in the treatment of children with pharyngo-conjunctival fever. Methods： Two hundreds and fifty-seven children with pharyngo-conjunctival fever were randomly divided into treatment group and control group,and two groups were given antipyretic treatment. The treatment group received Pudilan Xiaoyan oral liquid for 5 to 10 m L each time,3 times a day,while the control group was treated with ganciclovir 5 mg/kg in everyday by intravenous infusion,and both groups were treated for 5 days. Results： The total effective rate of treatment group and control group were respectively 92.6%（112/121） and 93.4%（127/136）,without any statistically significant difference（ P〈0.05）; and the compliance of treatment group was higher than that of control group（ P〈0.01）. Conclusion： Pudilan Xiaoyan oral liquid is effective in treatment of children with pharyngo-conjunctival fever. The curative efficacy of ganciclovir and Pudilan Xiaoyan oral liquid are comparable,yet Pudilan Xiaoyan oral liquid has better treatment compliance and is more acceptable to children and parents,which is worthy of clinical application.

关 键 词：咽结膜热 蒲地蓝消炎口服液 更昔洛韦 儿童 

分 类 号：R725.6[医药卫生—儿科]