母亲成熟卵巢畸胎瘤与胎儿不成熟骶尾部畸胎瘤共存1例及文献复习  

Co-existence of maternal mature ovarian teratoma and fetal immature sacrococcygeal teratoma: a case report and literatures review

作　　者：关怀 卢翠敏 尚丽新 GUAN Huai;LU Cui-min;SHANG Li-xin(Department of Obstetrics ＆ Gynecology,PLA Army General Hospital,Beijing 100700,China)

机构地区：[1]陆军总医院妇产科,北京100700

出　　处：《发育医学电子杂志》2018年第3期186-189,共4页Journal of Developmental Medicine (Electronic Version)

基　　金：全军"十一五"科技攻关课题(06G019)

摘　　要：目的探讨母亲成熟卵巢畸胎瘤与胎儿不成熟骶尾部畸胎瘤共存的临床特征。方法 2016年11月,陆军总医院妇产科收治1例母亲成熟卵巢畸胎瘤与胎儿不成熟骶尾部畸胎瘤共存患者,分析其临床特点。结果患者因"妊娠31^(+5)周,血压控制不理想,胎儿骶尾部包块"收入院。妊娠12周超声检查发现孕妇左侧卵巢4.1 cm×3.8 cm×3.6 cm大小囊肿。妊娠22+3周,超声检查提示胎儿骶尾部4.6 cm×5.0 cm×3.3 cm大小包块,随孕周进展,胎儿包块生长迅速。妊娠32^(+1)周时因无应激试验无反应型行剖宫产终止妊娠,新生儿为女性,生后1小时内死亡。新生儿肿瘤为实性、不规则,表面破溃,直径约15 cm,肿瘤使其臀部和左腿严重变形。病理检查提示,母亲肿瘤为囊性成熟畸胎瘤,胎儿肿瘤为不成熟畸胎瘤。结论母胎同时发生畸胎瘤罕见,本例为首次发现母亲成熟卵巢畸胎瘤与胎儿不成熟骶尾部畸胎瘤共存,胎儿预后极差。Objective To explore the clinical characteristics of the co-existence of maternal mature ovarian teratoma and fetal immature sacrococcygeal teratoma（SCT）. Methods The Obstetrics ＆ Gynecology Department of PLA Army General Hospital treated a pregnant woman diagnosed as co-existence of maternal mature ovarian teratoma and fetal immature sacrococcygeal teratoma in November 2016. The clinical characteristics of the case were analyzed. Results The patient was admitted to hospital because the blood pressure was not stable and there was a lump in the fetal sacrococcygeal region at 31＋5 gestational weeks. A cyst in left ovary of the woman was detected by ultrasound at 12 gestational weeks, which size was 4.1 cm×3.8 cm×3.6 cm. A sacrococcygeal lump of the fetus was found by ultrasound at 22＋3 gestational weeks, which size was 4.6 cm×5.0 cm×3.3 cm. With the gestation process, the sacrococcygeal lump of the fetus grew rapidly. Caesarean section was carried out because NST showed irresponsive result at 32＋1 gestational weeks. The newborn was female who died at one hour after birth. The tumor of the newborn was solid, irregular and festering at surface, which diameter was about 15 cm. The tumor caused severe deformation of the hip and left leg. Pathological biopsy revealed that the mother’s tumor was a cystic mature teratoma and the baby’s tumor was an immature teratoma. Conclusions The co-existence of maternal and fetal teratomas is rare. This report is the first case with co-existence of maternal mature ovarian teratoma and fetal immature SCT. The prognosis of the fetus is very poor.

关 键 词：共存 胎儿 母亲 畸胎瘤 

分 类 号：R714.5[医药卫生—妇产科学] R737.31[医药卫生—临床医学]