重组禽流感病毒(H5+H7)二价灭活疫苗免疫效果检测分析  

Analysis of Immune Effect of Recombinant Avian Influenza Virus(H5+H7) Bivalent Inactivated Vaccine

作　　者：吴学卫 刘亚娟 朱军 Wu Xuewei;Liu Yajuan;Zhu Jun(Animal Disease Prevention and Control Center of Anshun City in Guizhou Province,Anshun Guizhou 561000,China)

机构地区：[1]贵州省安顺市动物疫病预防控制中心,贵州安顺561000

出　　处：《贵州畜牧兽医》2018年第4期23-25,共3页Guizhou Journal of Animal Husbandry & Veterinary Medicine

摘　　要：为了评价不同厂家生产的6种重组禽流感病毒(H5+H7)二价灭活疫苗(H5N1 Re-8株+H7N9 Re-1株)对鸡的免疫效果,为疫苗的选择和制定切实可行的免疫程序提供参考,采用血凝抑制试验检测免疫二价苗后产生的抗体滴度,并进行多重比较和分析。结果:6种二价苗均可提供有效的免疫保护,但对H5和H7亚型的免疫保护存在差异,对H5亚型的免疫效果较好。To evaluate the inmmne effect of six recombinant AIV （H5＋H7） bivalent inactivated vaccines （H5N1 Re-8＋H7N9 Re-1 ） produced by different manufacturers on chickens for providing references for vaccine selection and development of practical inmmnization procedures, hemagglutination inhibition was used to detect the antibody titer after inmmne bivalent vaccine and significant tests wereconducted with nmltiple comparing. Results ：all the six recombinant bivalent vaccines can provide effective inmmne protection, but there is a difference in the inmmne protection of H5 and H7 subtypes, and the inmmne effect of H5 subtypes is better.

关 键 词：禽流感病毒 重组二价苗 抗体效价 

分 类 号：S859.797[农业科学—临床兽医学]