无创检测技术在新生儿血红蛋白检测中的应用  

Application of noninvasive hemoglobin monitoring in the neonatal ward

作　　者：陈坤[1] 刘利军[2] CHEN Kun;LIU Lijun(Baotou Medical College of Inner Mongolia University of Science and Technology,Baotou,Inner Mongolia 014040,China;Department of Neonatal,The Third Staff Hospital of Baogang Group,Baotou,Inner Mongolia 014010,China)

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014040 [2]包钢集团第三职工医院儿科,内蒙古包头014010

出　　处：《安徽医药》2018年第8期1481-1484,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨采用Masimo Radical-7脉搏血氧仪检测新生儿无创血红蛋白浓度的准确性,并探讨无创血红蛋白检测技术在新生儿病房中的应用。方法选取包钢集团第三职工医院新生儿病房2015年5~10月收治新生儿,在静脉血常规检测血红蛋白数值(t Hb)的基础上于采血前采用Masimo Radical-7脉搏血氧仪检测新生儿无创血红蛋白浓度(SpHb)值,将收集的157对有创静脉血t Hb与无创SpHb数据进行相关性及一致性的分析。结果 (1)t Hb和SpHb测定结果分别为(137.36±20.80)g·L-1和(136.68±21.35)g·L-1,n=157,t=0.758,P=0.449,差异无统计学意义。(2)pearson相关性分析结果显示t Hb与SpHb具有较好的相关性(r=0.858,P<0.001)。(3)Bland-Altman研究显示95%一致性的上下限(-21.4~22.8)g·L-1,其中有6个点(3.82%)在95%一致性界限外,151个点(96.18%)位于95%一致性界限内。结论采用Masimo Radical-7脉搏血氧仪检测新生儿无创血红蛋白浓度与有创采集的静脉血常规中血红蛋白浓度之间具有较好的相关性和一致性,对于诊断贫血具有良好的应用价值。Objective To investigate the accuracy of Masimo Radical-7 noninvasive hemoglobin monitoring in neonatal ward newborns,and discuss the value of noninvasive hemoglobin detection technology in neonates. Methods This study selected the newborns in the neonatal ward from the Third Staff Hospital of Baogang,who need to take venous blood routine examination during May 2015 to October2015. meanwhile,the total value of hemoglobin（t Hb） and noninvasive hemoglobin values（SpHb） were recorded by Masimo Radical-7 noninvasive hemoglobin monitoring,157 sets of data were collected,of which the correlation and consistency of the t Hb and SpHb were analyzed. Results The paired t test was used to analyze the experimental date. The test results of the t Hb and SpHb were respectively（137. 36 ± 20. 80） g·L^-1 and（136. 68 ± 21. 35） g·L^-1,n = 157,t = 0. 758,P = 0. 449. There was no significant between Masimo Radical-7 noninvasive hemoglobin instrument and SYSMEX XE5000 blood cell analyzer in measuring hemoglobin concentration. Pearson correlation analysis showed that t Hb and SpHb have good correlation（r = 0. 858,P 〈0. 001）. Bland-Altman study shows that the upper and lower limits of agreement of 95 % is（-21. 4-22. 8） g·L^-1. There are 6 points（3. 82%） outside the 95 % limits of agreement,151 points（96. 18%） in 95% limits of agreement. Conclusion Two measurement of neonatal hemoglobin concentration results are in good consistency,Masimo Radical-7 noninvasive hemoglobin monitoring is an effective complement to laboratory testing and neonatal anemia hemoglobin concentration diagnosis method.

关 键 词：无创监测 脉搏血红蛋白 总血红蛋白 新生儿病房 

分 类 号：R446.1[医药卫生—诊断学] R722.1[医药卫生—临床医学]