新生儿脐血IgE水平对幼儿不同过敏性疾病的预测作用  

The significance of umbilical cord blood IgE levels in the prediction of different allergic diseases in infants

作　　者：王节 纪东 桂晓钟 WANG Jie;JI Dong;GUI Xiaozhong(Otolaryngology Head and Neck Surgery,The Second People＇s Hospital of Wuhu,Wuhu,Anhui 241000,China)

机构地区：[1]芜湖市第二人民医院耳鼻咽喉头颈外科,安徽芜湖241000

出　　处：《安徽医药》2018年第8期1496-1498,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的研究新生儿的脐血IgE水平在幼儿不同过敏性疾病预测中的作用。方法收集新生儿的脐血标本,测定脐血IgE结果,随访至3~4岁,完善过敏相关症状的问卷调查。将过敏相关症状分成4组:无症状组、皮肤症状组、呼吸症状组和多症状组,观察脐血IgE水平在不同过敏症状组中的分布有无差别。结果过敏相关问卷调查结果如下:无症状组46例、皮肤症状组30例、呼吸症状组50例和多症状组79例。脐血IgE水平在不同过敏症状组中的分布经秩和检验,差异无统计学意义。结论新生儿脐血IgE水平可作为致敏指标,预测过敏性疾病的发生,但不能预测过敏相关的具体皮肤、呼吸等症状的发生。Objective To study the significance of umbilical cord blood IgE levels in the prediction of different allergic diseases in infants. Methods Newborn cord blood specimens were collected,and the cord blood IgE levels were measured. All the cases were followed up to 3-4 years old,then allergy-related symptoms were investigated. Allergy-related symptoms were divided into four groups： asymptomatic group,skin symptom group,respiratory symptom group and multi-symptom group. The distribution of IgE in umbilical cord blood in different allergic symptoms group was observed. Results Allergy related questionnaire survey results were as follows： 46 cases of asymptomatic group,30 cases of skin symptom group,50 cases of respiratory symptom group and 79 cases of multiple symptom group. Cord blood IgE levels in the distribution of different symptoms in the rank sum test,the difference with no statistically significant. Conclusion Newborn cord blood IgE levels can be used as sensitization indicators to predict the occurrence of allergic diseases,but can not predict allergy-related specific skin,respiratory and other symptoms.

关 键 词：新生儿 脐血IGE 幼儿 过敏性疾病 

分 类 号：R725.9[医药卫生—儿科]