儿童误服复方苯乙哌啶中毒7例  

Clinical analysis of 7 cases of children with compound diphenoxylate poisoning

作　　者：潘程宇 季兴[2] PAN Chengyu;JI Xing(Department of Digestive,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanfing University of Chinese Medicine,Nanjing,Jiangsu 210028,China;Department of Pharmacy,Children＇s Hospital of Nanjing Medical University,Nanjing,Jiangsu 210008,China)

机构地区：[1]南京中医药大学附属中西医结合医院消化内科,江苏南京210028 [2]南京医科大学附属儿童医院药学部,江苏南京210008

出　　处：《安徽医药》2018年第8期1573-1575,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的分析总结复方苯乙哌啶的中毒原因、临床表现、实验室检查结果、救治要点,以汲取经验教训。方法采用回顾性调查方法,分析2012年8月至2015年8月共7例误服复方苯乙哌啶导致中毒的儿童的临床治疗。结果经综合治疗,7例患儿中,6例救治成功,自动出院1例,痊愈5例,好转1例,治愈率71.43%。出院1个月后随访的6例患儿,未见症状反复。结论过量服用复方苯乙哌啶可造成中毒,大剂量时可产生严重并发症,危及生命。一旦发现,及时就治,采取综合性治疗方法,一般预后良好。同时指导家长加强对儿童的管理及监护。Objective To analyze and sum up the clinical manifestation,the effect of naloxone on children with poisoning of Compound Diphenoxylate and the prevention of children from intoxication. Methods The clinical data of 7 cases with Diphenoxylate poisoning who were treated in hospital from August 2012 to August 2015,were collected,arranged and analyzed. Results Using comprehensive treatment,especially Naloxone for treatment,among 7 cases,6 cases were successfully treated,1 case was discharged from hospital,5 cases were cured,1 case was improved. The curerate was 71. 43 %. 6 cases were followed up for 1 months after discharge,and no recurrence. Conclusion Diphenoxylate poisoning can cause toxicity,severe complications,or even death. Early diagnosis,comprehensive treatment be taken in time,especially Naloxone,was the key of treating children with Diphenoxylate poisoning. At the same time,the parents should be guided to strengthen the management and monitoring of children.

关 键 词：复方苯乙哌啶 误服 中毒 儿童 

分 类 号：R725.9[医药卫生—儿科]