尿流率计校准装置标准水流及其流量稳定性  

Uroflowmeter calibration device:standard water flow and its stability

作　　者：王莉新[1,2] 姬军[1,2] 高佳硕[2] 肖宏[2] Wang Li-xin;Ji Jun;Gao Jia-shuo;Xiao Hong(College of Biomedical Engineering,Southern Medical University,Guangzhou 510515,Guangdong Province,China;Medical Engineering Department of the 305^th Hospital of PLA,Beijing 100017,China)

机构地区：[1]南方医科大学生物医学工程学院,广东省广州市510515 [2]解放军第三0五医院医学工程科,北京市100017

出　　处：《中国组织工程研究》2018年第22期3569-3574,共6页Chinese Journal of Tissue Engineering Research

基　　金：军事计量建标科研项目“尿动力分析仪检定装置建标”(军装计2016[599]); 军事医学计量科研专项“尿动力分析仪检测技术研究”(2012-JL1-016)

摘　　要：背景:目前以数字信号处理器和齿轮泵为核心的尿流率计校准装置,由于设计中未考虑齿轮泵的脉动和泄露问题,仅利用齿轮泵转速数据拟合出的流量和流率数据对尿流率计进行校准,会对尿流率计校准结果产生错误引导。目的:在现有尿流率计校准装置基础上,利用数字信号处理定时器控制齿轮泵运转时间,使齿轮泵输出流量和流率均固定的标准水流,测量标准水流的流量,并对测量结果进行分析,以检验装置产生的标准水流能否用于临床对尿流率计进行校准。方法:使用B2000S电子天平,由不同测量人员在不同的时间测量校准装置产生的标准水流流量,利用SPSS20.0软件画出测量结果的分布直方图,观察测量结果的分布形态;利用系统分析的方法,分析影响测量结果不确定度的来源,计算测量结果的不确定度参数。结果与结论:(1)由不同测量人员在不同时间测量得到各流率下的标准水流流量值符合正态分布,流率为15 mL/s时,标准差最大,为0.549 m L;流率为10 mL/s时,标准差最小,为0.147 mL,说明校准装置产生的标准水流流量值波动性很小,水流流率、流量稳定性很高,可用多次测量结果的平均值作为标准水流流量最佳估计值;(2)系统分析显示,流率为50 mL/s时,不确定度参数最大,为0.75 mL;流率为10 mL/s时,不确定度参数最小,为0.29 m L,满足标准装置与被量器具之间不确定度量传比小于1∶3的要求,可用于临床对尿流率计进行校准。BACKGROUND： As the gear pump＇s leakage and pulsation are not taken into account to the design of the uroflowmeter calibration device composed of digital signal processor（DSP） and gear pump, a wrong result will be produced if we just calibrate the urinary flow meter with the theory flow data that work out by the recorded data of the gear pump＇s rotate speed.OBJECTIVE： Based on the designed uroflowmeter calibration device, using DSP timer to control the operation time of the gear pump to obtain a standard water flow with fixed rate and quantity, to measure the quantities of each standard water flow and to analyze the measurement results in order to test if the standard water flows produced by the uroflowmeter calibration device are suitable to calibrate urine flow rate in clinic. METHODS： The quantity of each standard water flow was measured by B2000 S scales in different time by different experimenters. SPSS 20.0 software was then used to draw the distribution histogram of each standard water flow measurement results. We also analyzed the factors affecting the uncertainty of the measurement results, and calculated the uncertainty of the results by systematic analysis. RESULTS AND CONCLUSION：（1） The quantities of each standard water flow measured by different experimenters in different time were consistent with normal distribution. The maximum stand deviation was 0.549 mL at the flow rate of 15 mL/s, and the minimum stand deviation was 0.147 mL at the flow rate of 10 mL/s. This indicates that the standard water flow produced by the uroflowmeter calibration device has a very high stability, both in flow rate and in flow volume. Therefore, the mean value of the multiple measurement results can be used as the best estimated value of the standard water flow.（2） The uncertainty of the measurement results were calculated by systematic analysis. The uncertainty was 0.75 mL in maximum at the rate of 50 mL/s, and 0.29 mL in minimum at the rate of 10 mL/s, which meets the requirement that the maximum

关 键 词：尿动力学 校准 组织工程 医学工程 尿流率计校准装置 标准水流 稳定性 不确定度 生物材料 

分 类 号：R318[医药卫生—生物医学工程]