参芍片联合温胆汤治疗心胆气虚型失眠症的临床观察  

The clinical research to treat insomnia of qi-deficiency of heart and gallbladder by Wendan Decoction with Shenshao tablet

作　　者：关慧泉 刘艳骄[2] GUAN Hui-quan 1, LIU Yan-jiao 2.(1 Adminstration office of outpatient department Beijing Xuanwu Traditional Chinese Medical Hospital, Beijing 100050, China; 2 Division of Sleep Medicine Guang＇anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China)

机构地区：[1]北京市宣武中医医院门诊办公室,北京100050 [2]中国中医科学院广安门医院睡眠医学科,北京100053

出　　处：《临床和实验医学杂志》2018年第14期1535-1538,共4页Journal of Clinical and Experimental Medicine

摘　　要：目的研究参芍片联合温胆汤治疗心胆气虚型失眠的临床疗效。方法前瞻性收集门诊心胆气虚型失眠患者100例,以数字随机表法分为实验组(温胆汤合参芍片)50例和对照组(单用温胆汤)50例,比较治疗开始前,治疗后2周、治疗后4周的匹兹堡睡眠质量指数(PSQI)积分和中医症状积分;并进行疗效评价。结果实验组第4周的有效率分别为96%,对照组第4周的有效率为84%,差异有统计学意义(P<0.05)。实验组4周的PSQI评分及中医症状评分均明显低于对照组,差异有统计学意义(P<0.05),提示治疗组优于对照组。结论参芍片温胆汤联合应用治疗明显心血管系统症状的心胆气虚型失眠患者,在改善患者的失眠症状,也能同时改善其失眠所导致的心血管系统症状。Objective To investigate the therapeutic effect of Wendan Decoction combining with Shenshao tablet on insomnia patients with qi-deficiency of heart and gallbladder. Methods 100 patients with qi-deficiency of heart and gallbladder from outpatient department of insomnia, were randomly divided into a treatment group treated by Wendan Decoction and Shenshao tablet and a control group treated by Wendan Decoction and placebo by random number table, comparing the Pittsburgh Sleep Quality Index （PSQI） and TCM symptom scores at the beginning of treatment, 2 weeks and 4 weeks of treatment duration, evaluating therapeutic effect. Results Efficiency of treatment group at 4 weeks was 96% and 84% in control group, difference was statistically significant （ P 〈0.05）. The difference of PSQI and TCM symptoms scores in each group at the 4 weeks of treatment duration also were statistically significant （ P 〈0.05）. It demonstrated that the effect of treatment group was better than that of the control group. Conclusion Shenshao Tablet combining with Wendan Decoction alleviated insomnia status of qi-deficiency of heart and gallbladder patients with obvious cardiovascular symptoms, may also ameliorating cardiovascular symptoms due to insomnia at the same time.

关 键 词：失眠症 心胆气虚证 温胆汤 参芍片 

分 类 号：R256.23[医药卫生—中医内科学]