颈动脉狭窄患者的椎动脉血流动力学改变  

The hemodynamics changes of vertebral artery in patients with carotid artery stenosis

作　　者：刘卫勇 叶磊[1] 丁作鹏 李喆[1] 胡春梅 汪林 朱娅娟 刘乐 Liu Weiyong,Ye Lei,Ding Zuopeng,Li Zhe,Hu Chunmei,Wang Lin,Zhu Yajuan,Liu Le(Department of Ultrasound,South District,the First Affiliated Hospital of University of Science and Technology of China,Hefei 230036, China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)南区超声医学科,合肥230036

出　　处：《中国临床保健杂志》2018年第4期477-479,共3页Chinese Journal of Clinical Healthcare

基　　金：安徽省科技厅资助课题(1401045018)

摘　　要：目的探讨颈动脉狭窄(CAS)患者椎动脉血流动力学改变。方法对65例住院患者行颈动脉超声检查,测量颈动脉内膜中层厚度(IMT)及椎动脉血流流速,并分析CAS椎动脉血流动力学改变的危险因素。结果依据颈动脉血管狭窄超声诊断标准分为CAS组21例(32.3%),非颈动脉狭窄组(NCAS)44例(67.7%)。CAS组IMT厚度大于非CAS组(P<0.05),CAS组的双侧椎动脉收缩期峰值流速(PSV)均大于非CAS组(P<0.05),而双侧椎动脉内径及阻力指数之间差异无统计学意义。logistic回归分析显示双侧椎动脉的PSV为CAS的危险因素。结论 CAS引起椎动脉血流动力学变化。Objective To investigate the changes of hemodynamics of vertebral artery in patients with carotid artery stenosis（ CAS）. Methods A total of 65 subjects have been enrolled into the study cohort. Carotid intima-media thickness（ IMT）,and vertebral artery flow velocity were measured by ultrasound. Risk factors of hemodynamics changes in the vertebral artery were identified in patients with CAS. Results According to the ultrasound diagnostic criteria for vascular stenosis,21 cases（ 32. 3%） were classified into CAS group and 44 cases（ 67. 7%） in non-carotid artery stenosis group（ NCAS）. The IMT in CASs was thicker than that in NCASs（ P 〈 0. 05）. The peak systolic velocities（ PSV）of bilateral vertebral arteries in CASs were thicker than that in NCASs（ P 〈 0. 05）. However,there were no significant difference in the diameters and RI between CASs and NCASs. Logistic regression analysis showed that PSVs of vertebral artery were a risk factor for CAS. Conclusion CAS impaires hemodynamics of vertebral artery,and significantly increases blood flow velocity in vertebral artery.

关 键 词：颈动脉狭窄 椎底动脉供血不足 血流动力学 危险因素 

分 类 号：R543.4[医药卫生—心血管疾病] R445.1[医药卫生—内科学]