丁苯酞序贯疗法对脑梗死患者血copeptin及临床疗效的影响  

The Effect of Butylphthalide Sequential Therapy on Serum Copeptin and Clinical Efficacy in Patients With Acute Cerebral Infaiction

作　　者：庄源[1] 魏广宽[1] ZHUANG Yuan;WEI Guangkuan(The Second Ward of Neurology Department,Heilongjiang Provincial Hospital,Harbin Heilongjiang 150036,China)

机构地区：[1]黑龙江省医院神经内科二病房,黑龙江哈尔滨150036

出　　处：《中国卫生标准管理》2018年第11期80-81,共2页China Health Standard Management

基　　金：黑龙江省卫生计生委科研课题(2017-497)

摘　　要：目的探讨丁苯酞序贯疗法对急性脑梗死患者血和肽素(copeptin)及临床疗效的影响。方法选取我院收治的急性脑梗死患者病例100例,随机分对照组和观察组各50例。对照组采用常规药物治疗,观察组在常规治疗基础上采取丁苯酞序贯治疗,共3个月。治疗期间于7 d和90 d分别对比患者脑卒中评分(NIHSS)和血copeptin水平。结果治疗后对比对照组,观察组患者血copeptin水平、NIHSS评分降低;观察组同组患者治疗后90 d与7 d相比较,血copeptin水平、NIHSS评分降低。结论丁苯酞序贯疗法能降低急性脑梗死患者血copeptin水平,恢复神经功能。Objecive To explore the effect of butylphthalide sequential therapy on serum copeptin and clinical efficacy in patients with acute cerebral infaiction. Methods 100 patients with acute cerebral infaiction were selected in neurology department in our hospital. They were randomly divided into observation group（n =50） and control group（n =50）. The control group was treated with the rountine treatment, while the observation group was treated with butylphthalide sequential therapy. The total duration of the two groups was 3 months. During the treatment of 7 d and 90 d, NIHSS（America Nation Institutes of Health Stroke, and the level of copeption was compared between two groups of patients. Results Compared with the control group after the treatment, the level of copeption and the score of NIHISS was lower; 90 d after the treatment compared with 7 d of the observation group,the level of copeption and the score of NIHISS was lower. Conclusion The treatment of butylphthalide sequential therapy can reduce the level of copeptin obviously, and thus improving neurological function.

关 键 词：丁苯酞序贯疗法 脑梗死 急性 和肽素 疗效 影响 

分 类 号：R971[医药卫生—药品]