平台颜色对大鼠Morris水迷宫训练成绩的影响  

The influence of platform color on the learning and memory performance of rats in Morris water maze

作　　者：周海东[1] 陈益君[1] 朱浩[1] ZHOU Haidong;CHEN Yijun;ZHU Hao(Department of Anesthesiology,Ningbo First Hospital,Ningbo 315010,China)

机构地区：[1]宁波市第一医院麻醉科,浙江宁波315010

出　　处：《中国现代医生》2018年第13期25-27,169,共4页China Modern Doctor

基　　金：浙江省中医药科学研究基金资助项目(2015ZA186);浙江省宁波市自然科学基金(2016A610155)

摘　　要：目的探讨平台颜色改变对大鼠水迷宫成绩的影响。方法选择成年雄性SD大鼠36只随机分为两组,分别置于蓝色平台(蓝色组,n=18)和白色平台(白色组,n=18)的水迷宫,每天训练4次,连续训练6 d,记录每次训练的潜伏期作为学习成绩,第7天通过水迷宫空间探索实验检测大鼠的空间记忆能力。结果定位航行实验显示两组大鼠在首日训练平均逃避潜伏期差异无统计学意义(P>0.05),蓝色组大鼠每天的潜伏期均短于白色组,且第3天和第4天差异有统计学意义(P<0.05),空间探索实验结果显示两组大鼠无明显差异(P>0.05)。结论蓝色平台组大鼠的学习能力提升速度快于白色平台组。Objective To investigate the influence of platform color on the learning and memory performance of rats in Morris water maze. Methods 36 adult male SD rats were randomized into two groups and put in water mazes with blue platform（blue group, n=18） and white platform（white group, n=18） respectively. The rats were trained 4 times per day for 6 days. The performance was indicated by escape latency in each training. The spatial memory ability of rats was assessed through spatial probe on the 7th day. Results No significant difference of average escape latency was found in rats of two groups in the place navigation in the training on the first day（P〈0.05）. Escape latency on each day of rats in blue group was shorter than that of rats in white group. Significant difference of escape latency was noticed on the 3rd and 4th day between two groups. There was no significant difference in the results of spatial probe in rats of two groups（P〈0.05）. Conclusion The improvement of learning ability in rats of blue group is faster than that in rats of white group.

关 键 词：平台 颜色 MORRIS水迷宫 训练成绩 

分 类 号：G861.1[文化科学—体育训练] R338[文化科学—体育学]