急性白血病合并脓毒症患者的抗感染治疗策略及用药分析  

Anti-infective Treatment Strategies and Drug Use Analysis for Patient with Acute Leukemia and Sepsis

作　　者：邓艳辉[1,2] 肖轶雯 DENG Yanhui;XIAO Yiwen(Department of Pharmacy,the Second Xiangya Hospital of Central South University,Changsha 410013,China;Department of Pharmacy,the Third Affiliated Hospital of Southern Medical University,Guangzhou 510630,China)

机构地区：[1]中南大学湘雅二医院药学部,长沙410013 [2]南方医科大学第三附属医院药学部,广州510630

出　　处：《医药导报》2018年第7期898-901,共4页Herald of Medicine

摘　　要：目的探讨急性白血病合并脓毒症患者的抗感染治疗策略,并对其用药进行分析,为临床合理用药提供参考。方法临床药师参与会诊1例急性白血病合并脓毒症患者,从药物选择、剂量、疗效及不良反应等方面进行分析,协助医师制定个体化抗感染给药方案,并提供药学监护。结果临床药师针对患者病程中不同阶段存在的致病菌,对抗感染治疗方案进行调整,使患者感染得到有效控制。结论临床药师参与医疗团队,发挥药学专业优势,协助医师调整并优化治疗方案,可最大程度减少药物相互作用的发生,确保临床治疗安全、有效。Objective To explore the anti-infective treatment strategies of an acute leukemia patient combined with sepsis,and analyze drug use,so as to provide reference for clinical rational drug use. Methods Clinical pharmacists participated in the drug therapy in a case of acute leukemia patient combined with sepsis,and analyzed drug variety,dosage,efficacy and adverse reactions,then assisted the doctors to formulate individualized dosage regimen and provide pharmaceutical care. Results Clinical pharmacists adjusted the anti-infective treatment according to the pathogenic bacteria in different stages of disease.So the patient＇s infection could be effectively controlled. Conclusion Clinical pharmacists should participate in the medical team,give full play to the advantages of pharmacy specialty,and assist doctors to adjust and optimize the treatment plan,which could minimize the occurrence of drug interactions and ensure the safety and effectiveness of clinical therapy.

关 键 词：白血病 急性 脓毒症 临床药师 抗感染治疗 药学监护 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]