针药并用治疗耐克罗米芬型多囊卵巢综合征不孕症临床研究  

Clinical Study of Acupuncture plus Medication for Infertility in Clomiphene Citrate-resistant Polycystic Ovary Syndrome

作　　者：阮婴丹 严越台 魏若涵 沈丹[1] RUAN Ying-dan, YAN Yue-tai, WEI Ruo-han, SHEN Dan.(Taizhou First People＇s Hospital of Zhejiang Province, Taizhou 318020, China)

机构地区：[1]浙江省台州市第一人民医院,台州318020

出　　处：《上海针灸杂志》2018年第7期769-772,共4页Shanghai Journal of Acupuncture and Moxibustion

摘　　要：目的观察针灸配合促性腺激素(hMG)序贯低剂量方案治疗耐克罗米芬(CC)型多囊卵巢综合征(PCOS)不孕症的疗效。方法耐CC型PCOS不孕症患者57例,随机分成对照组(单纯药物组28例)和针药组(针灸+药物治疗29例)。比较两组之间绒毛膜促性腺激素(HCG)注射日优势卵泡(平均卵泡直径14～18 mm)数目、成熟卵泡(直径≥18 mm)数目、雌二醇(E2)水平,hMG用量、排卵率、妊娠率、单胎率以及卵巢过度刺激综合征(OHSS)的发生率。结果针药组hM G用量、OHSS发生率均少于对照组,排卵率、临床妊娠率均高于对照组,差异有统计学意义(P<0.05)。结论针灸配合hMG序贯低剂量方案治疗PCOS合并不孕症具有较好疗效。Objective To observe the therapeutic efficacy of acupuncture-moxibustion plus sequential low-dose human menopausal gonadotropin（h MG） in treatment of infertility in clomiphene citrate（CC）-resistant polycystic ovary syndrome（PCOS）. Method Fifty-seven patients with infertility caused by CC-resistant PCOS were randomized into a control group（medication group with 28 cases） and an acupuncture-medication group（acupuncture-moxibustion plus medication group with 29 cases）. The two groups were compared with each other in the number of dominant follicle（average diameter 14-18 mm）, the number of mature follicle（diameter ≥18 mm） and the level of estradiol（E2） on the day of human chorionic gonadotropin, as well as the total consumption of h MG, ovulation rate, pregnancy rate, singleton pregnancy rate and occurrence of ovarian hyperstimulation syndrome（OHSS）. Result Compared with the control group, the acupuncture-medication group had lower total consumption of h MG and occurrence of OHSS, and higher ovulation and pregnancy rates, and the differences were statistically significant（P〈0.05）. Conclusion Acupuncture-moxibustion plus sequential low-dose h MG can produce a satisfactory efficacy in treatment of infertility caused by PCOS.

关 键 词：多囊卵巢综合征 针灸疗法 不育 女性 针药并用 

分 类 号：R246.3[医药卫生—针灸推拿学]