早期目标导向镇静联合有创无创序贯机械通气治疗AECOPD伴严重呼吸衰竭患者的临床观察  

Clinical observation of early goal directed sedation combined with invasive non-invasive sequential mechanical ventilation in the treatment of AECOPD with severe respiratory failure

作　　者：张春林[1] 张朝贵[1] Zhang Chunlin;Zhang Zhaogui(ICU,the Second People＇s Hospital of Yibin City,Sichua)

机构地区：[1]宜宾市第二人民医院ICU,四川644000

出　　处：《中国社区医师》2018年第19期95-95,97,共2页Chinese Community Doctors

摘　　要：目的:探讨早期目标导向镇静(EGDS)联合有创无创序贯治疗AECOPD伴严重呼吸衰竭患者的疗效。方法:收治AECOPD伴发呼吸衰竭患者46例,随机分为治疗组和对照组。治疗组采用早期目标导向镇静联合有创无创序贯机械通气方案,对照组采用常规镇静及机械通气方案,比较两组治疗效果。结果:治疗组入住ICU时间、总机械通气时间、谵妄发生率、VAP发生率和院内死亡率均显著优于对照组(P<0.05)。结论:目标导向镇静联合有创无创序贯机械通气治疗AECOPD伴呼吸衰竭的患者能减少入住ICU时间、机械通气时间,降低病死率,从而改善预后。Objective：To explore the clinical effect of early goal directed sedation（EGDS） combined with invasive non-invasive sequential mechanical ventilation in the treatment of AECOPD with severe respiratory failure.Methods：46 patients with AECOPD and severe respiratory failure were selected,they were randomly divided into the treatment group and the control group,the treatment group was treated with early goal directed sedation combined with invasive non-invasive sequential mechanical ventilation,the control group was treated with conventional sedation and mechanical ventilation,we compared the therapeutic effects of the two groups.Results：In the treatment group,ICU stay time,total mechanical ventilation time,delirium incidence,VAP incidence and hospital mortality rate were significantly better than those in the control group（P〈0.05）.Conclusion：The application of early goal directed sedation（EGDS） combined with invasive non-invasive sequential mechanical ventilation in the treatment of AECOPD with severe respiratory failure can reduce ICU stay time,mechanical ventilation time and mortality,so as to improve the prognosis.

关 键 词：早期目标导向镇静 序贯通气 慢性阻塞性肺疾病急性加重 

分 类 号：R563.8[医药卫生—呼吸系统]