BuMA支架在急诊PCI治疗老年和非老年心肌梗死患者中的长期疗效和安全性研究  

Long-term curative effect and safety of BuMA stent in emergency PCI for elderly and non-elderly patients with acute myocardial infarction

作　　者：李雪蛟[1] 罗军[1] 张刚[1] 张杨[1] 蔡立英 田攀[1] 张龙飞[1] 杨梅[1] 曹雪滨[1] Li Xuejiao;Luo Jun;Zhang Gang;Zhang Yang;Cai Liying;Tian Pan;Zhang Longfei;Yang Mei;Cao Xuebin(Department of Cardiology,Chinese PLA 252 Hospital,Baoding 071000,China.)

机构地区：[1]解放军252医院心内科,保定071000 [2]河北蠡县县医院心内科,蠡县071400

出　　处：《中国循证心血管医学杂志》2018年第4期445-447,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

基　　金：全军后勤计划延续项目(CBJ13J002);全军保健课题(15BJZ05)

摘　　要：目的观察国产Bu MA支架在急性心肌梗死(AMI)患者行急诊经皮冠状动脉介入治疗术(PCI)后的长期疗效和安全性。方法收集2015年1月~2015年12月于解放军第252医院行急诊PCI的急性心肌梗死患者89例,根据发病年龄将患者分为老年组(≥60岁)和非老年组(<60岁),回顾性分析两组患者的临床特点、PCI后支架血栓以及主要心脏不良事件的发生率等。结果老年组与非老年组在高血压、糖尿病等临床资料方面无统计学差异,但老年组女性患者的比例远高于非老年组(25.5%vs.5.3%,P=0.01)。随访结果显示,老年组和非老年组患者主要不良事件率分别为13.0%、8.6%,全因死亡率为10.9%、8.6%,靶病变血运重建率(TLR)和非靶血管血运重建率为20%、14.3%,两者比较均无统计学意义。结论国产Bu MA支架在急诊PCI治疗老年和非老年AMI患者应用中均具有较好的长期疗效和安全性。Objective To observe the long-term curative effect and safety of domestic Bu MA stent in patients with acute myocardial infarction（AMI） after emergency percutaneous coronary intervention（PCI）. Methods AMI patients（n=89） undergone emergency PCI were chosen from Chinese PLA 252 Hospital from Jan. 2015 to Dec. 2015, and then divided, according to their age, into elderly group（age≥60） and non-elderly group（age60）. The clinical features, in-stent thrombosis and incidence of major adverse cardiovascular events（MACE） after PCI were retrospectively analyzed in 2 groups. Results There were no statistical difference in clinical materials including hypertension and diabetes between elderly group and non-elderly group, but percentage of female patients was significantly higher in elderly group than that in non-elderly group（25.5% vs. 5.3%, P=0.01）. The results of followup showed that MACE incidence was 13.0% in elderly group and 8.6% in non-elderly group, all-cause mortality was 10.9% in elderly group and 8.6% in non-elderly group, and target lesion revascularization rate（TLR） or nonTLR was 20% in elderly group and 14.3% in non-elderly group. The comparison between 2 groups had no statistical significance. Conclusion The domestic Bu MA stent has higher long-term curative effect and safety during emergency PCI in elderly and non-elderly patients with AMI.

关 键 词：药物洗脱支架 急性心肌梗死 急诊 经皮冠状动脉介入治疗 

分 类 号：R542.22[医药卫生—心血管疾病]