术前应用复方碘溶液对非毒性巨大甲状腺肿手术的影响  

Effect of taking compound Iodine solution preoperatively to operation of nontoxic huge goiter

作　　者：胡洪生 孙少华 沈丰 武伦 吴红伟 周文波 HU Hong-sheng;SUN Shao-hua;SHEN Feng;WU Lun;WU Hong-wei;ZHOU Wen-bo(Department of Thyroid Center,Dongfeng Hospital of Hubei University of Medicine（Shiyan 442000,China)

机构地区：[1]湖北医药学院附属东风医院甲状腺诊疗中心,湖北十堰442000

出　　处：《中国现代普通外科进展》2018年第5期365-368,共4页Chinese Journal of Current Advances in General Surgery

基　　金：湖北省教育厅中青年人才项目(Q20162112);十堰市科技局(16Y61)

摘　　要：目的:研究复方碘溶液术前应用对非毒性巨大甲状腺肿手术的影响。方法:将湖北医药学院附属东风医院2013年1月—2016年6月收治的68例非毒性巨大甲状腺肿患者随机分为实验组和对照组两组,实验组38例,术前应用复方碘溶液;对照组30例,术前未应用复方碘溶液等特殊准备。比较两组患者手术时间、术中出血量、术后术腔引流量、术后血钙水平、甲状旁腺激素(PTH)水平、喉返神经损伤比例。结果:39例行全甲状腺或近全甲状腺切除术患者,其中实验组手术时间、术中出血量、术后术腔引流量明显低于对照组(P<0.05),而术后血钙、PTH水平明显高于对照组(P<0.05),喉返神经损伤比例差异无统计学意义(P>0.05)。29例行甲状腺大部切除术患者,实验组手术时间、术中出血量、术后腹腔引流量明显低于对照组(P<0.05);但术后血钙、PTH水平及喉返神经损伤比例,两组差异无统计学意义(P>0.05)。结论:术前运用复方碘溶液能够大大减少非毒性甲状腺肿患者手术时间、出血量,减少手术并发症发生率,降低非毒性甲状腺肿的手术难度。Objective： To study the effect of compound Iodine solution preoperatively to operation of nontoxic huge goiter. Method： 68 cases of nontoxic huge goiter were randomly divided to experimental group and control group during January 2013 to June 2016. 38 patients in experimental group were received compound Iodine solution before operation, while 30 patients in control group were not received compound Iodine solution. Then collected and compared the data of time consumed in operation, blood loss during operation, volume of drainage, level of serum calcium and PTH postoperative and the ratio of recurrent laryngeal nerve injury. Result： 39 patients undergoing total thyroidectomy and near total resection, Time consumed in operation, blood loss during operation,volume of drainage postoperative of experiment group were significant lower than control group（P0.05）. While level of serum calcium and PTH postoperative of experiment group were remarkable higher than control group（P0.05）. The ratio of recurrent laryngeal nerve injury had no significant difference（P〈0.05）. 29 patients undergoing bilateral thyroidectomy, Time consumed in operation, blood loss during operation, volume of drainage postoperative of experiment group were significant lower than control group（P〉0.05）. While level of serum calcium, PTH postoperative and the ratio of recurrent laryngeal nerve injury had no significant difference（P〉0.05）. Conclusion： It is taking Compound Iodine solution before operation of nontoxic huge goiter that reduced time consume in operation,blood loss during operation, volume of drainage and the occurrence of operative complications.It could decrease the difficult of operation nontoxic huge goiter.

关 键 词：复方碘溶液 非毒性甲状腺肿 甲状腺切除术 

分 类 号：R653[医药卫生—外科学]