两种钙剂型治疗系统性红斑狼疮患者早期激素继发股骨头坏死的临床观察  

Clinical observation of liquid calcium and solid calcium in the treatment of systemic lupus erythematosus patients with early stage steroid-induced femoral head necrosis

作　　者：陈辉 孙乐栋[2] 梅奕洁 CHEN Hui;SUN Le-Dong;MEI Yi-Jie(Traditional Chinese Medical Hospital of Gaoming District,Foshan 528500,China;Zhujiang Hospital of Southern Medical University,Guangzhou 510280,China)

机构地区：[1]佛山市高明区中医院,广东佛山528500 [2]南方医科大学珠江医院,广东广州510280

出　　处：《转化医学电子杂志》2018年第8期11-13,共3页E-Journal of Translational Medicine

摘　　要：目的:观察液体钙与固体钙两种不同钙制剂治疗系统性红斑狼疮患者早期激素继发股骨头坏死的临床疗效。方法:将符合系统性红斑狼疮患者早期激素继发股骨头坏死标准的60例患者随机分为液体钙组(n=30)和固体钙组(n=30),除原发病常规激素治疗外,液体钙组给予液体钙治疗,固体钙组给予固体钙治疗。2组均治疗6个月。结果:治疗3个月、6个月时固体钙组Harris评分均高于液体钙组(P<0.05);治疗6个月固体钙组总有效率93.33%,高于液体钙组的73.33%(P<0.05)。且固体钙价格相对较低。结论:在治疗系统性红斑狼疮激素性股骨头坏死早期中,固体钙优于液体钙,性价比高,疗效确切。Objective： To observe the two calcium form in the treatment of systemic lupus erythematosus（ SLE） patients with early steroid induced femoral head necrosis. Methods： Sixty systemic lupus erythematosus（ SLE） patients with steroid-induced femoral head necrosis were randomly divided into liquid calcium group and solid calcium group. In addition to glucocorticoid therapy,the liquid calcium group was given liquid calcium treatment,and the solid calcium group was given solid calcium therapy for six months. Results： The Harris score of solid calcium group was higher than that of liquid calcium group at 3 months and 6 months after treatment（ P0.05）. At 6 months after treatment,the total effective rate of solid calcium group was 93. 33%,which was higher than 73. 33% of liquid calcium group（ P 0.05）. And the price of solid calcium is relatively low. Conclusion： In the early stage of steroid-induced femoral head necrosis in SLE,solid calcium is superior to liquid calcium with high cost-effectiveness and definite curative effect.

关 键 词：系统性红斑狼疮 激素性股骨头坏死 液体钙 固体钙 

分 类 号：R751[医药卫生—皮肤病学与性病学]