Influence of Many-Month Exposure to Light with Shifted Wave Range and Partial Fullerene Hyperpolarization on the State of Elderly Mice  

作　　者：Sergiy A. Gulyar Zynaida A. Tamarova 

机构地区：[1]Department of General Physiology of Nervous System, Bogomoletz Institute of Physiology National Academy of Sciences ofUkraine, Kiev 401601, Ukraine [2]International Medical Innovation Center Zepter, Kiev 02152, Ukraine

出　　处：《Journal of US-China Medical Science》2018年第1期16-25,共10页美中医学（英文版）

摘　　要：Part of the unidirectional light waves （background polarization） due to the passage through the layer of fullerene molecules, acquires the properties of an ordered concentrated nano-photonic flow, called hyperpolarized. The aim was to investigate the effect of prolonged illumination of an animal with natural daylight passing through a fullerene filter, on behavior, physiological health indices and life expectancy. A long 8-month experiment was conducted on 12 male mice at the age of 1 year. Half of them were constantly under ＂fullerene＂ light （experimental group）, the rest--under natural light （control）. The spectrum of light passing through the fullerene filter was characterized by a weakened short-wavelength range and power density. Weekly we determined the body weight, recorded motor activity （open field test）, dynamics of natural behavioral reactions （sleeping, eating, running, washing）. It was found that after 9 weeks of observation the body weight in the control group mlimals began to decrease gradually （one of the signs of aging）. At the same time, the average body weight in the animals of the experimental group remained at the same level or even increased. The maximum difference between the two groups occurred 32 weeks after the start of the experiment. The body weight of ainmals receiving fullerene light was 38.25 g （20.5% increase） in this period, while in the control group it fell down to 27.42 g （a decrease of 13.8%）. The test ＂open field＂ showed that as the natural aging of mlimals continues their motor activity decreases. However, in the control group, this process is faster than in animals under the ＂fullerene＂ light. After 8 weeks of observation, the mobility of animals in the experimental group was significantly higher than in the control group. It is proved that the ＂fullerene＂ light preserves the natural behavior of animals （sleeping, eating behavior, etc.）. The animals of the experimental group lived for a total of 1,032 days, and the control

关 键 词：FULLERENE HYPERPOLARIZATION LIGHT aging motor activity body weight natural behavior of mice open field test 

分 类 号：R151[医药卫生—营养与食品卫生学] R914[医药卫生—公共卫生与预防医学]