围术期临床研究的结局评估:以患者为中心的新理念  

Outcome assessment in perioperative clinical studies: a new patient-centered concept

作　　者：杨谦梓[1] 薄禄龙 YANG Qianzi, BO Lulong(1Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi＇an 710032; 2 Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai 200433, Chin)

机构地区：[1]第四军医大学附属西京医院麻醉与围术期医学科,陕西西安710032 [2]海军军医大学附属长海医院麻醉学部,上海200433

出　　处：《麻醉安全与质控》2018年第4期185-188,共4页Perioperative Safety and Quality Assurance

基　　金：上海市优秀青年医学人才培养计划(2017YQ015)

摘　　要：临床研究通常选用由医学专家制定的客观指标对结果进行评估,然而随着"以患者为中心"的医疗模式深入开展,特别是加速术后康复、舒适化麻醉、精准麻醉等理念的逐渐推广,围术期临床研究越来越关注患者的疼痛、心理感受、残疾和社会能力丧失等由患者报告的结局。本文结合近期多项国际大型临床研究,介绍"以患者为中心"的临床研究结局评估新理念,并探讨其在围术期研究中的应用及面临的问题,为未来的广泛应用提供参考。Clinical studies typically employ objective parameters identified by medical experts to evaluate medical outcomes. However,due to the development of ＂patient-centered＂medical paradigm with concepts such as Enhanced Recovery After Surgery,Comfort Anesthesia and Precision Anesthesia,particular attention is shifted toward patient-reported outcomes in perioperative clinical studies,such as pain,psychological feelings,physical disability,and loss of social capacity. In the current paper,we analyzed a number of recently published large-scale international clinical studies,introduced the new concept of＂patient-centered outcome＂and discussed its indications and potential problems in the clinical study of perioperative medicine,in order to facilitate future applications.

关 键 词：临床研究 围术期医学 以患者为中心 研究结局 

分 类 号：R614[医药卫生—麻醉学]