感染和炎性反应与早产发病机制研究进展  

Research progress on infection and inflammatory response in preterm birth

作　　者：李莉[1] 陈巧媛[1] LI Li;CHEN Qiao-yuan(Dept.of Prenatal Diagnosis Center,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing 100026,China)

机构地区：[1]首都医科大学附属北京妇产医院产前诊断中心,北京100026

出　　处：《基础医学与临床》2018年第9期1348-1351,共4页Basic and Clinical Medicine

基　　金：首都医科大学基础与临床李桓英联合基金(17JL-L05)

摘　　要：早产指妊娠37周之前分娩,可导致新生儿发病和死亡。虽然妊娠相关并发症的潜在原因很多,但感染与炎性反应是早产的主要原因。早产是一个具有全球意义的公共卫生问题,然而感染因素、免疫途径在早产的发病机制中的作用迄今仍不明确。Preterm birth refers to delivery before 37 weeks of gestation,which can cause neonatal illness and death.Although there are many potential causes of pregnancy related complications,infection and inflammation have been identified as an important risk factor for preterm birth. Preterm birth is a global public health problem,but the role of infection factors and immune pathways in the pathogenesis of preterm birth is still not clear.

关 键 词：感染 炎性反应 早产 分子机制 

分 类 号：R392.3[医药卫生—免疫学]