基于因子分析和Logistic回归的304例老年溃疡性结肠炎证候量化诊断研究  

Study on Quantitative Diagnostic Criteria of 304 Cases of Senile Ulcerative Colitis Based on Factor Analysis and Logistic Regression Analysis

作　　者：刘艳[1] 李毅[1,2] 许永攀 王捷虹 唐梦凡 孙婳[1] LIU Yan;LI Yi;XU Yong-pan;WANG Jie-hong;TANG Meng-fan;SUN Hua(Shaanxi University of Traditional Chinese Medicine,Xianyang Shaanxi 712046,China;The Affiliated Hospital of Shaanxi University tff Traditional Chinese Medicine,Xianyang Shaanxi 712000,China)

机构地区：[1]陕西中医药大学,陕西咸阳712046 [2]陕西中医药大学附属医院,陕西咸阳712000

出　　处：《中医药导报》2018年第16期34-36,40,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：陕西省教育厅研究项目(2017JK0222);陕西中医药大学科研基金项目(2015QN17);陕西省科技厅研究项目(2013JQ4009)

摘　　要：目的:探讨因子分析和Logistic回归分析在老年溃疡性结肠炎中医证候研究中的应用,为老年溃疡性结肠炎证候分类及制定诊断标准提供一定的科学依据。方法:采用自拟《老年溃疡性结肠炎的中医证候流行病学调查表》收集老年溃疡性结肠炎患者304例,并行因子分析和Logistic回归分析。结果:因子分析结果表明,老年溃疡性结肠炎证候特征为活动期以大肠湿热证和寒湿内盛证为主,缓解期以脾胃虚弱证、肝郁脾虚证、脾肾阳虚证、阴虚肠燥证等为主;运用多元Logistic回归分析,得出老年溃疡性结肠炎各证候的症状量化指标。结论:因子分析和Logistic回归分析结合的多元统计方法可用于老年溃疡性结肠炎中医证候分类及量化诊断研究,为该病的证候诊断标准研究提供了一种新的方法。Objective： To explore the application of factor analysis and Logistic regression analysis in the study of TCM Syndromes of senile ulcerative colitis, and to provide a scientific basis for the classification of ul- cerative colitis syndrome and the development of diagnostic criteria. Methods： Using self-made senile ulcer^aive colitis TCM syndrome epidemiology questionnaire, 304 cases of senile ulcerative colitis were collected and ana- lyzed by factor analysis and cluster analysis method. Results： Using the method of factor analysis, the basic TCM Syndromes of the active senile ulcerative colitis are obtained as damp heat syndrome and cold dampness syndrome; the basic TCM Syndromes of senile ulcerative colitis in remission are obtained as the spleen and stomach Qi deficiency, liver stagnation and spleen deficiency, Yang deficiency of spleen and kidney and Yin deficiency and intestinal dryness. Using multiple logistic regression analysis, the symptom of ulcerative colitis was quantified. Conclusion： Multivariate statistical methods of factor analysis and Logistic regression analysis can be used for the classification and quantitative diagnosis of senile ulcerative colitis, which also provides a new method to study the syndrome diagnosis standard of this disease.

关 键 词：溃疡性结肠炎 证候 因子分析 LOGISTIC回归分析 

分 类 号：R256.3[医药卫生—中医内科学]