HIV/AIDS合并NTM病的研究进展  

Advances in the study of non-tuberculous mycobacteria disease in patients with HIV/AIDS

作　　者：田景辉 吴利先 TIAN Jing-Hui;WU Li-xian(Department of Microbiology and Immunology of Dali University,Dali 671000,Yunnan,China)

机构地区：[1]大理大学基础医学院微生物与免疫学教研室,云南大理671000

出　　处：《中国病原生物学杂志》2018年第7期804-804,F0003,F0004,共3页Journal of Pathogen Biology

基　　金：国家自然科学基金项目(No.81760357)

摘　　要：近年来,非结核分枝杆菌(Non-tuberculosis mycobacteria,NTM)病在全球的患病率呈快速增长的趋势,且随着HIV/AIDS患者的出现,由非结核分枝杆菌引起的疾病的发生率升高,同时也使人们认识到非结核分枝杆菌病的重要性。HIV/AIDS患者免疫力低下,死亡率高,更容易被NTM感染,从而加速HIV/AIDS患者死亡。因此,尽快对非结核分枝杆菌进行诊断,不仅具有流行病学的意义,而且对降低HIV/AIDS患者的死亡率具有重要意义。本文就近几年关于HIV/AIDS合并NTM病的研究进展做一综述。Over the past few years,the worldwide prevalence of non-tuberculous mycobacteria（NTM）disease has increased rapidly,and the incidence of diseases caused by NTM has increased as more patients with HIV/AIDS have been identified.People have also been made aware of the significance of NTM disease.Patients with HIV/AIDS have compromised immunity,a high mortality rate,and are more susceptible to infection with NTM,thereby accelerating their deaths.Therefore,the prompt diagnosis of NTM is not only of epidemiological significance but is also crucial to reducing the mortality rate of patients with HIV/AIDS.This article reviews recent advances in the study of NTM disease in patients with HIV/AIDS.

关 键 词：非结核分枝杆菌病 艾滋病 分类 影响机制 展望 综述 

分 类 号：R378.911[医药卫生—病原生物学]