氧化钕:分布特征及毒理学研究进展  

Toxicological studies on neodymium oxide

作　　者：杨宁 纪乐[1] 姜珊 樊鸿星 刘东杰[1] 吴涛[1] 杨静[1] 吴刚[1] YANG Ning;JI Le;JIANG Shan;FAN Hong-xing;LIU Dong-jie;WU Tao;YANG Jing;WU Gang(School of Preclinical and Forensic Medicine,Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou,lnner Mongolia 014040,China;Pharmaceutical Inspection Department,Wulanchabu Medical College,Ulanqab,Inner Mongolia 012000,China）.)

机构地区：[1]内蒙古科技大学包头医学院基础医学与法医学院,内蒙古包头014040 [2]乌兰察布医学高等专科学校药学检验系,内蒙古乌兰察布012000

出　　处：《环境与职业医学》2018年第8期770-773,共4页Journal of Environmental and Occupational Medicine

基　　金：内蒙古自治区自然科学基金项目(编号:2015MS0868);内蒙古自治区研究生科研创新项目[编号:S201710127(Y01)]

摘　　要：氧化钕是最重要的稀土氧化物,随着使用量日益增多,其可能产生的毒性已经引起了人们的关注。本文介绍了氧化钕的体内代谢过程、体内外毒性作用以及可能作用机制等的研究进展,提出了现阶段研究的不足,并对今后氧化钕的毒性研究进行了展望。Neodymium oxide is recognized as one of the most important rare earth oxides.Its usage is increasing and has raised great concerns about its potential toxic actions.This article described the metabolic process in vivo,the toxic effects both in vivo and in vitro,and possible action mechanism of neodymium oxide,pointed out the limitations in current studies,and proposed directions for future research on neodymium oxide toxicity.

关 键 词：氧化钕 肺损伤 细胞毒性 毒理学 

分 类 号：R99[医药卫生—毒理学]