蒙药朱如拉及线叶菊抑真菌实验研究  

Antifungal Experiment Report About Mongolian Medicine Zhurula Xianyeju

作　　者：王星 张秀丽 柳莉 

机构地区：[1]包头市中心医院皮肤性病科,内蒙古包头014040 [2]内蒙古自治区人民医院皮肤性病科,内蒙古呼和浩特010000 [3]内蒙古国际蒙医院皮肤性病科,内蒙古呼和浩特010000

出　　处：《内蒙古医学杂志》2018年第6期641-643,共3页Inner Mongolia Medical Journal

摘　　要：目的观察蒙药朱如拉、线叶菊对临床常见致病性真菌的抑菌效果。方法采用药基混合法和琼脂扩散法对常见致病真菌进行蒙药朱如拉、线叶菊体外抗菌活性、最低抑菌浓度测定。结果体外抑菌试验显示,朱如拉醇提水提物混合和朱如拉加线叶菊醇提水提物混合联用对糠秕马拉色菌最小抑菌浓度测定(minimal inhibitory concentration,MIC)均为3.125 mg/ml,朱如拉水提取物混合和线叶菊醇提取物混合对糠秕马拉色菌MIC均为6.25 mg/ml;朱如拉线叶菊联用对红色毛癣菌MIC为6.25 mg/ml。结论蒙药朱如拉、线叶菊对真菌均具有抗真菌作用,尤其对红色毛癣菌和马拉色菌有很强的抗真菌作用,有潜力成为一种有研究价值的抗真菌新药。Objective To study inhibitory action of Mongolian medicine zhurula、xianyeju common pathogenic fungi.Methods The antimicrobial activity and the minimum inhibitory concentration of common pathogenic fungi by Mongolian medicine which were detected by the Drug based mixing method and AGAR diffusion method.Results The experiments revealed the mixture of zhurula and Zhurula Xieyeju on the In vitro studies were 3.125 mg/ml,The MIC OF zhurula and xieyeju were individual 6.25 mg/ml.Conclusions Zhurula、xianyeju have good antifungal effects,especially on Trichophyton rubrum and Malassezia fungus,so it will become a valuable research on antifungal drug.

关 键 词：蒙药 红色毛癣菌 马拉色菌 

分 类 号：R285.6[医药卫生—中药学]